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献血者缺铁状况的治疗:硫酸铁与琥珀酸铁蛋白的对照研究。

Treatment of iron deficiency conditions in blood donors: controlled study of iron sulphate versus iron protein succinylate.

作者信息

Landucci G, Frontespezi S

机构信息

USL No. 6 Piana di Lucca, UO Immunohaematology and Blood Transfusion, Italy.

出版信息

J Int Med Res. 1987 Nov-Dec;15(6):379-82. doi: 10.1177/030006058701500608.

DOI:10.1177/030006058701500608
PMID:3325320
Abstract

Iron protein succinylate is a new iron preparation for oral administration. In a controlled study versus iron sulphate in 40 blood donors with low levels of stored iron, treatment for 30 days with iron protein succinylate resulted in greater iron absorption compared to the reference drug. Serum iron concentration significantly increased compared with baseline values only in patients given iron protein succinylate. The amount of stored iron, evaluated by serum ferritin levels, significantly increased in both treatment groups.

摘要

琥珀酸铁蛋白是一种新型口服铁制剂。在一项针对40名储存铁水平较低的献血者进行的与硫酸铁对比的对照研究中,与参比药物相比,琥珀酸铁蛋白治疗30天导致铁吸收增加。仅在给予琥珀酸铁蛋白的患者中,血清铁浓度与基线值相比显著增加。通过血清铁蛋白水平评估的储存铁量在两个治疗组中均显著增加。

相似文献

1
Treatment of iron deficiency conditions in blood donors: controlled study of iron sulphate versus iron protein succinylate.献血者缺铁状况的治疗:硫酸铁与琥珀酸铁蛋白的对照研究。
J Int Med Res. 1987 Nov-Dec;15(6):379-82. doi: 10.1177/030006058701500608.
2
Serum iron concentrations following administration of two different iron preparations.两种不同铁制剂给药后的血清铁浓度。
J Int Med Res. 1987 Nov-Dec;15(6):374-8. doi: 10.1177/030006058701500607.
3
Iron Protein Succinylate in the Management of Iron Deficiency Anemia: A Comparative Study with Ferrous Sulphate at Low and High Therapeutic Doses.琥珀酸铁蛋白治疗缺铁性贫血的研究:与低、高治疗剂量硫酸亚铁的对比研究
Nutrients. 2021 Mar 17;13(3):968. doi: 10.3390/nu13030968.
4
Evaluation of the siderohaemic curve after loading administration of iron--protein--succinylate to gastrectomized subjects: a controlled study.胃切除患者服用铁-蛋白-琥珀酸酯负荷给药后高铁血症曲线的评估:一项对照研究。
J Int Med Res. 1990 May-Jun;18(3):225-7. doi: 10.1177/030006059001800307.
5
[Treatment and prevention of iron deficiency anemia].
Klin Med (Mosk). 1989 Aug;67(8):109-14.
6
[Determination of serum ferritin: ideas for avoiding induced ferropenia in blood donors].[血清铁蛋白的测定:避免献血者发生诱发性铁缺乏症的思路]
Sangre (Barc). 1994 Feb;39(1):9-14.
7
Ferritin versus ferrous sulphate preparations: a controlled study in sideropaenic patients.
Pharmatherapeutica. 1986;4(10):673-8.
8
Accumulation of storage iron in patients treated for iron-deficiency anaemia.缺铁性贫血患者治疗后储存铁的蓄积
Br Med J. 1975 Apr 12;2(5962):64-6. doi: 10.1136/bmj.2.5962.64.
9
Comparison of anti-anaemic effects of iron protein succinylate (ITF 282) and ferrous sulfate in the rat.
Drugs Exp Clin Res. 1990;16(7):333-42.
10
[A new therapeutic approach to iron deficiency].
Clin Ter. 1987 Oct 15;123(1):25-39.

引用本文的文献

1
Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors.口服或胃肠外补充铁剂以减少献血者的延期献血、缺铁和/或贫血。
Cochrane Database Syst Rev. 2014 Jul 3;2014(7):CD009532. doi: 10.1002/14651858.CD009532.pub2.