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献血者缺铁状况的治疗:硫酸铁与琥珀酸铁蛋白的对照研究。

Treatment of iron deficiency conditions in blood donors: controlled study of iron sulphate versus iron protein succinylate.

作者信息

Landucci G, Frontespezi S

机构信息

USL No. 6 Piana di Lucca, UO Immunohaematology and Blood Transfusion, Italy.

出版信息

J Int Med Res. 1987 Nov-Dec;15(6):379-82. doi: 10.1177/030006058701500608.

Abstract

Iron protein succinylate is a new iron preparation for oral administration. In a controlled study versus iron sulphate in 40 blood donors with low levels of stored iron, treatment for 30 days with iron protein succinylate resulted in greater iron absorption compared to the reference drug. Serum iron concentration significantly increased compared with baseline values only in patients given iron protein succinylate. The amount of stored iron, evaluated by serum ferritin levels, significantly increased in both treatment groups.

摘要

琥珀酸铁蛋白是一种新型口服铁制剂。在一项针对40名储存铁水平较低的献血者进行的与硫酸铁对比的对照研究中,与参比药物相比,琥珀酸铁蛋白治疗30天导致铁吸收增加。仅在给予琥珀酸铁蛋白的患者中,血清铁浓度与基线值相比显著增加。通过血清铁蛋白水平评估的储存铁量在两个治疗组中均显著增加。

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