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经皮腔内血管成形术治疗血栓形成的血液透析瘘:单中心 1 年随访经验。

Percutaneous angioplasty in the treatment of thrombosed hemodialysis fistulas: A single-center experience with 1 year of follow-up.

机构信息

Department of Cardiology, Sakarya University Faculty of Medicine, Adapazarı, Turkey.

Department of Nephrology, Sakarya University Faculty of Medicine, Adapazarı, Turkey.

出版信息

Turk Kardiyol Dern Ars. 2020 Nov;48(8):754-759. doi: 10.5543/tkda.2020.33027.

Abstract

OBJECTIVE

Thrombosis of a hemodialysis arteriovenous fistula (AVF) is a serious complication that needs urgent treatment. Most cases are treated surgically, but recently, endovascular strategies have become a viable alternative. This study is an evaluation of the success and patency rate of percutaneous balloon angioplasty of thrombosed hemodialysis fistulas using a drug-coated balloon (DCB) contrasted with a standard balloon (SB).

METHODS

The data of 33 patients with a thrombosed native hemodialysis AVF treated percutaneously in a tertiary care center were analyzed retrospectively. Success of the procedure was defined as restoration of flow with less than 30% residual stenosis and resumption of dialysis through the hemodialysis AVF. The success rate of the procedure and the patency rate at 1, 6, and 12 months were evaluated. The effect on patency of a DCB was compared to that of a SB.

RESULTS

Twenty-five radiocephalic and 8 brachiocephalic thrombosed hemodialysis AVFs were treated during the study period. Flow was restored in 23 thrombosed fistulas, a success rate of 69.7%. The patency rate of successfully treated fistulas was 95.6% at 1 month, 76.1% at 6 months, and 57.9% at 12 months. Ten of the 23 re-established AVFs were treated with a DCB and the remainder were treated with a SB. The patency of the fistulas treated with a DCB was similar to that of a SB at 1 month (100% vs 92.3%, respectively; p=0.393). The patency rate of a DCB was greater than that of a SB at 6 months (88.9% vs 66.7%, respectively; p=0.258) and 12 months (75% vs 45.4%, respectively; p=0.219).

CONCLUSION

Percutaneous intervention for thrombosed hemodialysis AVFs is a safe, minimally invasive, and effective procedure. There was a positive trend in the patency rate of patients treated with a DCB at 6 and 12 months compared with a SB.

摘要

目的

血液透析动静脉瘘(AVF)血栓形成是一种严重的并发症,需要紧急治疗。大多数情况下需要手术治疗,但最近,血管内策略已成为一种可行的替代方法。本研究评估了使用药物涂层球囊(DCB)与标准球囊(SB)对血栓形成的血液透析瘘进行经皮腔内血管成形术的成功率和通畅率。

方法

回顾性分析了在三级保健中心接受经皮治疗的 33 例血栓形成的原生血液透析 AVF 患者的数据。该程序的成功定义为恢复血流,残余狭窄小于 30%,并且通过血液透析 AVF 恢复透析。评估了该程序的成功率和 1、6 和 12 个月的通畅率。比较了 DCB 对通畅率的影响与 SB 的影响。

结果

在研究期间,共治疗了 25 例头臂静脉 AVF 和 8 例臂头静脉 AVF 血栓形成。在 23 例血栓形成的瘘中恢复了血流,成功率为 69.7%。成功治疗的瘘管在 1 个月时的通畅率为 95.6%,在 6 个月时为 76.1%,在 12 个月时为 57.9%。在 23 例再建立的 AVF 中,有 10 例接受了 DCB 治疗,其余的则接受了 SB 治疗。用 DCB 治疗的瘘管的通畅率与 SB 相似,1 个月时分别为 100%和 92.3%(p=0.393)。6 个月和 12 个月时,DCB 的通畅率大于 SB(分别为 88.9%和 66.7%,p=0.258 和 75%和 45.4%,p=0.219)。

结论

经皮治疗血栓形成的血液透析 AVF 是一种安全、微创且有效的方法。与 SB 相比,用 DCB 治疗的患者在 6 个月和 12 个月时的通畅率有积极的趋势。

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