Department of Clinical Pharmacy and Outcomes Sciences (CPOS), University of South Carolina College of Pharmacy, Columbia, SC, USA.
Department of Clinical Pharmacy and Translational Science, University of Tennessee Health Science Center, Memphis, TN, USA.
AIDS Care. 2023 Aug;35(8):1076-1082. doi: 10.1080/09540121.2020.1849531. Epub 2020 Dec 1.
Clinical management of human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) is progressing to include chronic/metabolic complications, which may impose a significant economic burden on beneficiaries and Medicare. We assessed the national economic impact of comorbid Type-II Diabetes Mellitus (T2DM) on HIV/AIDS patients and potential raical disparities. This study was a cross-sectional study of Medicare database 2013-2017. Analytical sample included HIV/AIDS positive beneficiaries continuously enrolled in Part A/B. Total medical costs, prescription costs, inpatient costs, outpatient costs, out-of-pocket (OOP) costs, and Medicare costs were assessed from Medicare claims. Generalized linear models with log-link and gamma distribution were used to examine the impact of T2DM on different costs. A total of 2,509 eligible HIV/AIDS positive beneficiaries were identified of which 19.9% (=498) had T2DM. After adjusting for covariates, T2DM beneficiaries had higher inpatient costs: 63.34% (95% CI: 42.73%-86.94%), outpatient costs: 50.26% (95% CI: 30.70%-72.75%), Medicare costs: 27.95% (95% CI: 13.81%-43.84%), OOP costs: 59.15% (95% CI: 40.02%-80.92%), and total medical costs: 27.83% (95% CI: 14.27%-43.00%) than non-T2DM beneficiaries. Incremental costs were higher among African Americans than Caucasians. Comorbid T2DM mposes a significant economic burden on HIV/AIDS patients and Medicare, which is higheramong African Americans.
人类免疫缺陷病毒/获得性免疫缺陷综合征(HIV/AIDS)的临床管理正在发展为包括慢性/代谢并发症,这可能会给受益人及医疗保险带来重大经济负担。我们评估了合并 2 型糖尿病(T2DM)对 HIV/AIDS 患者的全国性经济影响和潜在的根本性差异。本研究是对 2013 年至 2017 年医疗保险数据库的横断面研究。分析样本包括连续参加 A 部分/B 部分的 HIV/AIDS 阳性受益人。从医疗保险索赔中评估总医疗费用、处方费用、住院费用、门诊费用、自付费用和医疗保险费用。使用对数链接和伽马分布的广义线性模型来检查 T2DM 对不同费用的影响。确定了 2509 名符合条件的 HIV/AIDS 阳性受益人,其中 19.9%(=498)患有 T2DM。在调整了协变量后,T2DM 受益人的住院费用更高:63.34%(95%CI:42.73%-86.94%),门诊费用更高:50.26%(95%CI:30.70%-72.75%),医疗保险费用更高:27.95%(95%CI:13.81%-43.84%),自付费用更高:59.15%(95%CI:40.02%-80.92%),总医疗费用更高:27.83%(95%CI:14.27%-43.00%)比非 T2DM 受益人。非裔美国人比白人的增量成本更高。合并 T2DM 给 HIV/AIDS 患者和医疗保险带来了重大的经济负担,而非裔美国人的负担更高。