Vangrinsven Emilie, Broux Olivier, Massart Laurent, Claeys Stephanie, Clercx Cécile, Billen Frédéric
Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Liège, Quartier Vallée 2, Avenue de Cureghem 3, 4000, Liège, Belgium.
Department of Biostatistics, Faculty of Veterinary Medicine, University of Liège, Quartier Vallée 2, Avenue de Cureghem 3, 4000, Liège, Belgium.
J Small Anim Pract. 2021 Mar;62(3):200-208. doi: 10.1111/jsap.13279. Epub 2020 Dec 1.
To determine whether there is a benefit of using pre- and postoperative antacid treatment in dogs undergoing surgery for brachycephalic syndrome. To assess the use of an obstruction manoeuvre during endoscopy for the detection of dynamic gastro-oesophageal junction abnormalities.
Thirty-six client-owned brachycephalic dogs were prospectively included in a randomised trial. Antacid treatment was randomly prescribed in 18 dogs before and after surgery while the other 18 dogs did not receive any gastrointestinal medical treatment. At presentation, at the time of surgery and at recheck, digestive clinical signs and gastro-oesophageal junction abnormalities were assessed using specific scores. Gastro-oesophageal junction abnormalities were assessed during endoscopy in standard conditions as well as during endotracheal tube obstruction. This manoeuvre was also applied in an unrelated control group.
The results suggest a beneficial effect of antacid treatment on the improvement of digestive clinical signs and lesions in dogs with brachycephalic syndrome undergoing surgery. At postsurgical control 83% of dogs had a digestive clinical score ≤1 in the treated group in contrast to 44% in the non-treated group and 39% of dogs had a gastro-oesophageal abnormalities score (during obstruction manoeuvre) ≤1 in the treated group in contrast to 16.7% in the non-treated group. The use of the obstruction manoeuvre during endoscopic assessment in a control group revealed that gastro-oesophageal junction movements are negligible in healthy animals.
The addition of antacid treatment during the pre- and postoperative period for brachycephalic dogs undergoing surgery may result in a faster and greater improvement in treated dogs. The obstruction manoeuvre is an interesting technique to improve detection of gastro-oesophageal junction abnormalities.
确定在接受短头综合征手术的犬中使用术前和术后抗酸治疗是否有益。评估在内镜检查期间使用阻塞操作来检测动态胃食管交界异常。
36只客户拥有的短头犬被前瞻性纳入一项随机试验。18只犬在手术前后被随机给予抗酸治疗，而另外18只犬未接受任何胃肠道药物治疗。在就诊时、手术时和复查时，使用特定评分评估消化临床体征和胃食管交界异常。在标准条件下以及气管插管阻塞期间通过内镜检查评估胃食管交界异常。该操作也应用于一个不相关的对照组。
结果表明抗酸治疗对接受手术的短头综合征犬的消化临床体征和病变改善有有益作用。在术后复查时，治疗组83%的犬消化临床评分≤1，而未治疗组为44%；治疗组39%的犬（在阻塞操作期间）胃食管异常评分≤1，而未治疗组为16.7%。在对照组的内镜评估期间使用阻塞操作显示，健康动物的胃食管交界运动可忽略不计。
在接受手术的短头犬的术前和术后期间添加抗酸治疗可能会使治疗的犬更快且更显著地改善。阻塞操作是一种用于改善胃食管交界异常检测的有趣技术。
