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早期动静脉内瘘(戈尔 ACUSEAL)置管的短期至中期结果:日本队列中 ACUSEAL 的使用经验。

Short- to midterm results of early cannulation arteriovenous grafts (Gore ACUSEAL) for hemodialysis: Experience with the ACUSEAL in a Japanese cohort.

机构信息

Department of Vascular Surgery, Fukuoka City Hospital, Fukuoka, Japan.

出版信息

J Vasc Access. 2022 Jan;23(1):75-80. doi: 10.1177/1129729820974250. Epub 2020 Dec 3.

Abstract

BACKGROUND

In patients without suitable vasculature for autologous arteriovenous fistula, vascular access using a prosthetic graft is an option for hemodialysis. Gore ACUSEAL Vascular graft is an early cannulation arteriovenous graft (AVG) that allows early puncture within 24 h after surgery. We aimed to report the outcomes of using this graft in patients from a single center.

METHODS

This study included 113 patients who underwent surgery for a new AVG using ACUSEAL, between December 2015 and December 2017, and were followed up. The primary outcomes were primary patency, assisted-primary patency, and secondary patency. Secondary outcomes were postoperative complications such as graft infection and steal syndrome.

RESULTS

Of the 113 patients, 60 were male and 53 were female. The average age was 74.4 ± 10.7 years. We could cannulate 69.1% of patients within 24 h. The average follow-up period was 20.1 ± 10.8 months. The primary patency rates after 3 months, 6 months, and 1 year were 76.2%, 60.4%, and 33.8%, respectively. The assisted-primary patency rates after 3 months, 6 months, and 1 year were 88.8%, 73.2%, and 58.9%, respectively. The secondary patency rates after 3 months, 6 months, and 1 year were 100%, 100%, and 98.8%, respectively. Fourteen patients (12.4%) developed graft infection and two patients (1.8%) developed steal syndrome.

CONCLUSION

In our study, ACUSEAL showed satisfactory patency and acceptable complication rates in the short to medium term, similar to previous studies. ACUSEAL is beneficial for surgeons who are familiar with using AVG and for medical staff who control bleeding after dialysis. However, due to the large outer diameter of the graft, surgical wounds might become dehiscent, and careful designing of the subcutaneous graft route is necessary. It might be possible to reduce the rate of graft infection by planning the site and skin incision.

摘要

背景

对于没有合适自体动静脉瘘血管的患者,使用移植物进行血管通路是血液透析的一种选择。戈尔 ACUSEAL 血管移植物是一种早期可穿刺的动静脉移植物(AVG),允许在手术后 24 小时内进行早期穿刺。我们旨在报告在单中心使用这种移植物的患者的结果。

方法

这项研究纳入了 2015 年 12 月至 2017 年 12 月期间接受 ACUSEAL 新 AVG 手术的 113 名患者,并对其进行了随访。主要结局是一期通畅率、辅助一期通畅率和二期通畅率。次要结局是术后并发症,如移植物感染和窃血综合征。

结果

113 名患者中,60 名男性,53 名女性,平均年龄 74.4±10.7 岁。我们可以在 24 小时内对 69.1%的患者进行穿刺。平均随访时间为 20.1±10.8 个月。术后 3 个月、6 个月和 1 年的一期通畅率分别为 76.2%、60.4%和 33.8%。术后 3 个月、6 个月和 1 年的辅助一期通畅率分别为 88.8%、73.2%和 58.9%。术后 3 个月、6 个月和 1 年的二期通畅率分别为 100%、100%和 98.8%。14 名患者(12.4%)发生移植物感染,2 名患者(1.8%)发生窃血综合征。

结论

在我们的研究中,ACUSEAL 在短期至中期表现出令人满意的通畅率和可接受的并发症发生率,与之前的研究相似。ACUSEAL 有利于熟悉使用 AVG 的外科医生和控制透析后出血的医护人员。然而,由于移植物的外径较大,手术伤口可能会裂开,因此需要仔细设计皮下移植物的路径。通过规划部位和皮肤切口,有可能降低移植物感染的发生率。

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