Silverman Montane B, Oliver Joshua J, Belcher Christopher N, Wray Jesse, Bridwell Rachel E
F. Edward Hebert School of Medicine, Uniformed Services University, 4301 Jones Bridge Rd, Bethesda, MD 20814, United States.
Department of Emergency Medicine, Madigan Army Medical Center, 9040A Jackson Ave, Joint Base Lewis-McChord, WA 98431, United States.
Am J Emerg Med. 2021 Jun;44:477.e1-477.e3. doi: 10.1016/j.ajem.2020.10.032. Epub 2020 Oct 21.
A pancreaticopleural fistula (PPF) is a rare condition that causes thoracic symptoms such as dyspnea and chest pain secondary to exudative pleural effusions. While PPF is a very rare complication with only 52 cases reported between 1960 and 2007, they typically occur in patients who are male, middle aged, and have a history of chronic alcohol use and chronic pancreatitis (Aswani and Hira, 2015; Francisco et al., n.d.; Valeshabad et al., 2018; Ali et al., 2009). The fistula between the pancreas and pleural cavity causes large, rapidly accumulating, and recurrent pleural effusions which cause symptoms that can be difficult to differentiate from other acute thoracic pathologies (Francisco et al., n.d.). As a result, it is essential that providers have a high index of suspicion for PPF in these appropriate populations. We present a case study to review the typical presentation, pathophysiology, and current approach to treatment of PPF. This case is unique as the patient had no known risk factors. Due to limited data on this topic, there are no evidence-based guidelines on this topic, leaving a variety of case reports to inform clinical management in the emergency department.
胰胸膜瘘(PPF)是一种罕见的病症,会导致因渗出性胸腔积液继发的呼吸困难和胸痛等胸部症状。虽然PPF是一种非常罕见的并发症,在1960年至2007年间仅报告了52例,但它通常发生在男性、中年且有长期饮酒史和慢性胰腺炎病史的患者中(阿斯瓦尼和希拉,2015年;弗朗西斯科等人,无日期;瓦莱沙巴德等人,2018年;阿里等人,2009年)。胰腺与胸膜腔之间的瘘管会导致大量、迅速积聚且反复出现的胸腔积液,这些积液所引发的症状可能难以与其他急性胸部疾病相区分(弗朗西斯科等人,无日期)。因此,医疗人员必须对这些合适人群中的PPF保持高度怀疑指数。我们呈现一个病例研究,以回顾PPF的典型表现、病理生理学及当前的治疗方法。该病例具有独特性,因为患者没有已知的危险因素。由于关于该主题的数据有限,目前尚无基于证据的指南,只能通过各种病例报告为急诊科的临床管理提供参考。