Biology Program, Bard College, Annandale-on-Hudson, New York 12504, USA.
Cold Spring Harb Protoc. 2021 Apr 1;2021(4):pdb.prot106914. doi: 10.1101/pdb.prot106914.
In teaching, the best exam questions are those that seem simple at first but can lead to deep and nuanced conversations. Similarly, to probe brain development, we should look for behaviors that are easy to evoke and quantify, but that are demanding, malleable, and inherently variable. Visual collision avoidance is an example of such a behavior; it is ecologically relevant, robust, and easy to record, but also nuanced and shaped by the sensory history of the animal. Here we describe how to set up a visual avoidance assay and how to use it to test sensory processing and sensorimotor transformations in the vertebrate brain.
在教学中，最好的试题是那些乍一看很简单，但却能引发深入而细致的讨论的试题。同样，为了探究大脑发育，我们应该寻找那些易于引起和量化，但又具有挑战性、可塑和固有变异性的行为。视觉回避就是这样一种行为；它具有生态相关性，稳健且易于记录，但也具有细微差别，并受到动物感官历史的影响。在这里，我们描述了如何设置视觉回避测定法，以及如何使用它来测试脊椎动物大脑中的感觉处理和感觉运动转换。
