Department of Internal Medicine, Singapore General Hospital, Singapore
Department of Infection Prevention and Epidemiology, Singapore General Hospital, Singapore.
Thorax. 2021 May;76(5):512-513. doi: 10.1136/thoraxjnl-2020-216083. Epub 2020 Dec 3.
Hospitalisations for acute exacerbations of COPD (AECOPD) carry significant morbidity and mortality. Respiratory viral infections (RVIs) are the most common cause of AECOPD and are associated with worse clinical outcomes. During the COVID-19 pandemic, public health measures, such as social distancing and universal masking, were originally implemented to reduce transmission of SARS-CoV-2; these public health measures were subsequently also observed to reduce transmission of other common circulating RVIs. In this study, we report a significant and sustained decrease in hospital admissions for all AECOPD as well as RVI-associated AECOPD, which coincided with the introduction of public health measures during the COVID-19 pandemic.
COPD 急性加重(AECOPD)住院治疗会带来严重的发病率和死亡率。呼吸道病毒感染(RVIs)是 AECOPD 的最常见原因,并与更差的临床结局相关。在 COVID-19 大流行期间,最初实施的公共卫生措施,如社交距离和普遍戴口罩,是为了减少 SARS-CoV-2 的传播;随后还观察到这些公共卫生措施也减少了其他常见循环 RVIs 的传播。在这项研究中,我们报告了 COVID-19 大流行期间实施公共卫生措施后,所有 AECOPD 以及与 RVI 相关的 AECOPD 住院人数显著且持续下降。