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正常压力脑积水:诊断延误。

Normal pressure hydrocephalus: Diagnostic delay.

机构信息

Escuela de Medicina, Universidad del Valle, Cali, Colombia.

Departamento de Psiquiatría, Hospital Universitario Psiquiátrico del Valle, Cali, Colombia.

出版信息

Biomedica. 2020 Dec 2;40(4):656-663. doi: 10.7705/biomedica.5382.

Abstract

INTRODUCTION

Normotensive hydrocephalus is a differential diagnosis in the evaluation of the dementia syndrome. The diagnostic protocols would allow detecting this pathology that has more effective treatment than other dementias.

OBJECTIVE

To describe a population with clinical suspicion of normal pressure hydrocephalus evaluated in a Colombian psychiatric hospital and discuss the possible reasons for its diagnostic and therapeutic delay.

MATERIALS AND METHODS

We conducted a retrospective study of medical records to identify patients with suspected normal pressure hydrocephalus during a 5-year period.

RESULTS

Thirty-five patients with suspected normal pressure hydrocephalus underwent diagnostic lumbar puncture and five of them were considered candidates for a peritonealvenous shunt, but none underwent this surgical procedure. After three to six months of the lumbar puncture, the gait pattern improved in 22.8% of the patients, cognition in 22.8%, and sphincter control in 11.4%. Improvement was not sustained in the long term (1 year) in any of them.

CONCLUSION

This study suggests the poor implementation of the protocols for evaluating patients with cognitive deficits and delays in the diagnosis of normal pressure hydrocephalus. A small number of patients were identified as candidates for treatment. Normal pressure hydrocephalus is a potentially reversible clinical entity with the placement of a peritoneal ventricular shunt, but delays in diagnosis and treatment have deleterious consequences for patients and their families.

摘要

引言

在评估痴呆综合征时,正常压力性脑积水是一种鉴别诊断。诊断方案可以检测出这种比其他类型痴呆更有效的治疗方法的疾病。

目的

描述在哥伦比亚一家精神病医院接受评估的具有临床疑似正常压力性脑积水的人群,并讨论其诊断和治疗延迟的可能原因。

材料和方法

我们对病历进行了回顾性研究,以确定在 5 年期间疑似正常压力性脑积水的患者。

结果

35 例疑似正常压力性脑积水患者接受了诊断性腰椎穿刺,其中 5 例被认为是腹膜静脉分流术的候选者,但没有进行该手术。腰椎穿刺后 3 至 6 个月,22.8%的患者步态模式改善,22.8%的认知功能改善,11.4%的括约肌控制改善。但在任何患者中,这种改善都没有在长期(1 年)内持续。

结论

本研究表明,评估认知功能障碍患者的方案实施情况不佳,且正常压力性脑积水的诊断存在延迟。只有少数患者被确定为治疗候选者。正常压力性脑积水是一种潜在可逆转的临床实体,通过放置腹膜脑室分流术可以治疗,但诊断和治疗的延迟对患者及其家属有不利影响。

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