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腹直肌肌皮瓣在外科肿瘤学缺损一期重建中的多功能性

Versatility of Rectus Abdominis Myocutaneous Flap in Primary Reconstruction of Defects in Surgical Oncology.

作者信息

Mirza Abid Ali, Srinivas Kodaganur Gopinath, Amarendra Shankarappa, Swamy Shivananda, Krishna Anand, Gopinath K S

机构信息

Omega Sushrutha Cancer Hospital, No. 8-5-11, Housing Board Colony, Opp. Old Power House, Karimnagar, Telangana State 500001 India.

HCG-Bangalore Institute of Oncology, 44/45-2, 2nd Cross, RRMR extension, Bangalore, Karnataka 560027 India.

出版信息

Indian J Surg Oncol. 2020 Dec;11(4):740-745. doi: 10.1007/s13193-020-01213-4. Epub 2020 Sep 17.

Abstract

With the advent of microvascular surgery, the choice of reconstruction following resection of the primary has an important bearing on the final functional and cosmetic outcome in surgical oncology. The vertical rectus abdominis myocutaneous (VRAM) flap is arguably the most widely used and versatile flap in reconstructive surgery. All patients undergoing a VRAM flap reconstruction following resection of their tumor in the Surgical Oncology Department of a tertiary cancer center from 2012 to 2019 were included in the study. Defects ranged from the breast (40), head and neck (10), groin (3), and perineum (5). The primary outcome measure was incidence of complete and partial flap necrosis, while incidence of hematoma, seroma, incisional hernia, wound dehiscence, and infection were secondary outcomes measured. The patients were followed up for a minimum period of 1 year. The incidence of complete flap necrosis was 5.1% (3) and partial loss 12% (7). Incidence of minor complications such as seroma was 13.7% (8), hematoma 6.8% (4), wound dehiscence 10.3% (6), and wound infection 5.1% (3). Incisional hernia and donor site wound-related complications were not seen in any. On binary regression analysis, the presence of diabetes mellitus, smoking, and the use of adjuvant treatment were associated significantly with increased odds of flap loss. This study demonstrates the versatility and reliability of the VRAM flap in primary reconstruction of defects in surgical oncology. Optimization of risk factors such as diabetes, smoking, and weight gain can reduce flap loss and improve outcomes.

摘要

随着微血管外科的出现,原发灶切除后的重建选择对肿瘤外科手术的最终功能和美容效果具有重要影响。腹直肌垂直肌皮瓣(VRAM瓣)可以说是重建手术中使用最广泛、用途最多的皮瓣。本研究纳入了2012年至2019年在一家三级癌症中心的外科肿瘤科接受肿瘤切除术后行VRAM瓣重建的所有患者。缺损部位包括乳房(40例)、头颈部(10例)、腹股沟(3例)和会阴(5例)。主要结局指标是皮瓣完全和部分坏死的发生率,而血肿、血清肿、切口疝、伤口裂开和感染的发生率则作为次要结局指标进行测量。对患者进行了至少1年的随访。皮瓣完全坏死的发生率为5.1%(3例),部分坏死为12%(7例)。血清肿等轻微并发症的发生率为13.7%(8例),血肿为6.8%(4例),伤口裂开为10.3%(6例),伤口感染为5.1%(3例)。未发现任何切口疝和供区伤口相关并发症。二元回归分析显示,糖尿病、吸烟以及辅助治疗的使用与皮瓣丢失几率增加显著相关。本研究证明了VRAM瓣在肿瘤外科手术缺损一期重建中的多功能性和可靠性。优化糖尿病、吸烟和体重增加等危险因素可减少皮瓣丢失并改善预后。

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