Sezgin Gulten, Coskun Mehmet, Apaydin Melda, Keceli Merter, Cetinoglu Kenan, Tavusbay Cengiz
Department of Radiology, Izmir Katip Celebi University Ataturk Training and Research Hospital, Izmir, Turkey.
Department of Radiology, Dr. Behçet Uz Child Disease and Pediatric Surgery Training and Research Hospital, University of Health Sciences, Izmir, Turkey.
J Med Ultrasound. 2020 Mar 26;28(3):169-172. doi: 10.4103/JMU.JMU_112_19. eCollection 2020 Jul-Sep.
The purpose of this retrospective study is to investigate the association of qualitative and semiquantitative strain elastography (SE) features with factors such as lesion size, skin-to-lesion distance, and patient's age in fibroadenomas and to discuss false-positive results.
A total of 120 lesions that were performed SE with histopathologically confirmed fibroadenoma were included in the study. All images were reviewed from the archiving system with a consensus of two radiologists. Tsukuba elasticity score was used for color scoring (from 1 to 5). Lesions with strain ratio (SR) ≥2.27 and color scale score of 4 or 5 were considered as false positive. The patients were divided into two groups according to the age: <50 and ≥50 years old. Regard of the size, lesions were divided into two groups: <15 mm and ≥15 mm. The distances of the lesions to the skin were also divided into two groups: <5 mm and ≥5 mm. Statistical analysis to identify associations between these groups and SR was carried out with Pearson Chi-square test and Fisher's exact test. The false-positive rates were calculated.
There was no statistically significant difference between patients' age, lesion size, skin-to-lesion distance, and SR values. The false-positive rate was 21.66% for SR, while it was 3.33% for color scale.
SR values of the fibroadenomas were not affected by factors such as age, lesion size, and depth. In addition, false-positive rates significantly decrease when color scale scores are evaluated for fibroadenomas.
本回顾性研究的目的是调查定性和半定量应变弹性成像(SE)特征与纤维腺瘤的病变大小、病变至皮肤距离和患者年龄等因素之间的关联,并讨论假阳性结果。
本研究纳入了120个经组织病理学证实为纤维腺瘤且进行了SE检查的病变。所有图像均从存档系统中调出,由两名放射科医生达成共识进行评估。采用筑波弹性评分进行彩色评分(1至5分)。应变率(SR)≥2.27且彩色量表评分为4或5分的病变被视为假阳性。患者按年龄分为两组:<50岁和≥50岁。根据大小,病变分为两组:<15 mm和≥15 mm。病变至皮肤的距离也分为两组:<5 mm和≥5 mm。采用Pearson卡方检验和Fisher精确检验进行统计分析,以确定这些组与SR之间的关联。计算假阳性率。
患者年龄、病变大小、病变至皮肤距离和SR值之间无统计学显著差异。SR的假阳性率为21.66%,而彩色量表的假阳性率为3.33%。
纤维腺瘤的SR值不受年龄、病变大小和深度等因素的影响。此外,对纤维腺瘤进行彩色量表评分时,假阳性率显著降低。