Yang Wenjing, Wang Guyan, Li He, Yan Xing, Ren Yaoyao, Wang Yue, Hu Haili, Song Xiaoli, Wan Ying, Wang Chengshuo, Lou Hongfei, Huang Qian, Wang Xiangdong, Zhang Luo
Department of Anesthesiology, Beijing TongRen Hospital, Capital Medical University, Beijing, China.
Department of Otolaryngology-Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China.
Int Forum Allergy Rhinol. 2021 Jun;11(6):993-1000. doi: 10.1002/alr.22734. Epub 2020 Dec 7.
In this study we compared intraoperative bleeding and regional cerebral oxygenation in patients with different degrees of the reverse Trendelenburg position (RTP) during endoscopic sinus surgery (ESS).
In total, 120 patients with chronic rhinosinusitis treated by ESS were randomly assigned to the following 4 groups: a horizontal position (HP) group, and 5°, 10°, and 15° RTP (5-RTP, 10-RTP, and 15-RTP, respectively) groups. The primary outcome was the Boezaart grading scale (BS). The cerebral oxygen saturation (ScO ), total blood loss, numerical rating scale (NRS) scores, and complications were also recorded.
The median BS values in the HP, 5-RTP, 10-RTP, and 15-RTP groups were 2.0, 2.0, 2.1, and 1.7, respectively. Multiple pairwise comparisons of the BS showed significant differences between the 15-RTP group and the other 3 groups (HP, 5-RTP, and 10-RTP). Regarding the NRS and bleeding rate, significant differences were found between the HP and 15-RTP groups. No difference was found in ScO among the 4 groups, and no cerebral desaturation events occurred in any group. No complications, including vital organ (heart, brain, and kidney) dysfunction problems, were reported in this study during hospitalization.
Compared with HP, 5-RTP, and 10-RTP, 15-RTP can improve visual clarity during ESS, and ScO is not affected by the degree of RTP. No cerebral deoxygenation or vital organ dysfunction was observed in this study. Therefore, we recommend 15-RTP with moderate deliberate hypotension for ESS.
在本研究中,我们比较了鼻内镜手术(ESS)期间不同程度头高脚低位(RTP)患者的术中出血情况和局部脑氧合情况。
总共120例接受ESS治疗的慢性鼻窦炎患者被随机分为以下4组:平卧位(HP)组,以及5°、10°和15°RTP(分别为5-RTP、10-RTP和15-RTP)组。主要观察指标为Boezaart分级量表(BS)。还记录了脑氧饱和度(ScO)、总失血量、数字评分量表(NRS)评分及并发症情况。
HP组、5-RTP组、10-RTP组和15-RTP组的BS中位数分别为2.0、2.0、2.1和1.7。BS的多重两两比较显示,15-RTP组与其他3组(HP组、5-RTP组和10-RTP组)之间存在显著差异。关于NRS和出血率,HP组和15-RTP组之间存在显著差异。4组之间ScO无差异,且任何组均未发生脑氧饱和度降低事件。本研究住院期间未报告包括重要器官(心脏、脑和肾)功能障碍问题在内的并发症。
与HP、5-RTP和10-RTP相比,15-RTP可提高ESS期间的视野清晰度,且ScO不受RTP程度的影响。本研究未观察到脑脱氧或重要器官功能障碍。因此,我们推荐在ESS中采用15-RTP并适度控制性低血压。