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开窗冷冻象鼻技术治疗急性A型主动脉夹层的临床转归。

Clinical outcomes of a fenestrated frozen elephant trunk technique for acute type A aortic dissection.

机构信息

Department of Cardiovascular Surgery, Nerima Hikarigaoka Hospital, Tokyo, Japan.

出版信息

Eur J Cardiothorac Surg. 2021 Apr 29;59(4):765-772. doi: 10.1093/ejcts/ezaa411.

Abstract

OBJECTIVES

We investigated the outcomes of a fenestrated frozen elephant trunk (FET) technique performed without reconstruction of one or more supra-aortic vessels for aortic repair in patients with acute type A aortic dissection.

METHODS

We investigated 22 patients who underwent the fenestrated FET technique for acute type A aortic dissection at our hospital between December 2017 and April 2020. The most common symptom was chest pain and/or back pain. Nine patients presented with malperfusion and 1 with cardiac arrest, preoperatively. A FET was deployed under hypothermic circulatory arrest and manually fenestrated under direct vision. Single fenestration was made in the FET in 15 patients, 2 fenestrations in 5 patients and a total fenestrated technique in 2 patients. Concomitant procedures were performed in 5 patients.

RESULTS

The cardiopulmonary bypass, aortic cross-clamp and hypothermic circulatory arrest times were 181 ± 49, 106 ± 43 and 37 ± 7 min, respectively. In-hospital mortality, stroke, or recurrent nerve injury did not occur in any patient. One patient developed paraparesis, which completely recovered at discharge. During the follow-up period (mean 18 ± 7 months), 1 patient died of heart failure. Fenestration site occlusion did not occur. Follow-up computed tomography (mean 12 ± 6 months postoperatively) revealed that the maximal aortic diameter remained unchanged at the levels of the distal end of the FET, the 10th thoracic vertebra and the coeliac artery; however, the aortic diameter was significantly reduced at the level of the pulmonary artery bifurcation.

CONCLUSIONS

The fenestrated FET technique is a simple, safe and effective procedure for selected patients with acute type A aortic dissection.

摘要

目的

我们研究了在急性 A 型主动脉夹层患者中,不重建一个或多个主动脉上腔血管,而采用开窗式冷冻象鼻技术进行主动脉修复的结果。

方法

我们研究了 2017 年 12 月至 2020 年 4 月期间在我院接受急性 A 型主动脉夹层开窗式冷冻象鼻技术治疗的 22 例患者。最常见的症状是胸痛和/或背痛。术前 9 例患者存在灌注不良,1 例患者出现心脏骤停。在低温体外循环下展开象鼻,并在直视下手动开窗。15 例患者在象鼻中进行了单个开窗,5 例患者进行了 2 个开窗,2 例患者进行了全开窗技术。5 例患者同时进行了其他手术。

结果

体外循环、主动脉阻断和低温体外循环时间分别为 181±49、106±43 和 37±7 分钟。住院期间无死亡、中风或膈神经损伤发生。1 例患者发生截瘫,出院时完全恢复。在随访期间(平均 18±7 个月),1 例患者死于心力衰竭。未发生开窗部位闭塞。随访 CT(术后平均 12±6 个月)显示,象鼻远端、第 10 胸椎和腹腔动脉水平的主动脉直径保持不变,但肺动脉分叉处的主动脉直径明显缩小。

结论

对于特定的急性 A 型主动脉夹层患者,开窗式冷冻象鼻技术是一种简单、安全和有效的手术方法。

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