Olson G E, Winfrey V P, Flaherty S P
Department of Cell Biology, Vanderbilt University, Nashville, Tennessee 37232.
Ann N Y Acad Sci. 1987;513:222-46. doi: 10.1111/j.1749-6632.1987.tb25012.x.
It is becoming increasingly evident that the different domains of the mammalian spermatozoa possess distinct cytoskeletal assemblies. In this paper we have discussed three assemblies, found in the acrosomal, postacrosomal, and midpiece segment, respectively. Each has a distinct substructure and associates with specific sperm-membrane systems. Their protein compositions are currently unidentified, and they may be comprised of sperm-specific polypeptides. Analysis of their formation and fate during sperm-egg interaction should provide valuable insight into their role in the development of cell polarity and in the membrane-mediated steps of fertilization.
越来越明显的是，哺乳动物精子的不同区域拥有独特的细胞骨架组装。在本文中，我们讨论了分别存在于顶体、顶体后和中段的三种组装。每种都有独特的亚结构，并与特定的精子膜系统相关联。它们的蛋白质组成目前尚未确定，可能由精子特异性多肽组成。分析它们在精卵相互作用过程中的形成和命运，应该能为它们在细胞极性发展以及受精的膜介导步骤中的作用提供有价值的见解。
