儿童急性淋巴细胞白血病合并铜绿假单胞菌性肌炎 1 例报告并文献复习
Pseudomonas aeruginosa Pyomyositis in a Child With Acute Lymphoblastic Leukemia: A Case Report and Review of Literature.
机构信息
Department of Medicine, Surgery, and Health Sciences, University of Trieste.
Institute for Maternal and Child Health-"IRCCS Burlo Garofolo," Trieste, Italy.
出版信息
J Pediatr Hematol Oncol. 2021 Aug 1;43(6):e795-e797. doi: 10.1097/MPH.0000000000002029.
BACKGROUND
We report the case of an 11-year-old girl with a recent diagnosis of common B-cell acute lymphoblastic leukemia who presented with Pseudomonas aeruginosa pyomyositis of the left lower limb during severe neutropenia associated with the induction phase of chemotherapy.
OBSERVATIONS
Presenting signs included fever, leg pain, and refusal to walk. Popliteal knee ultrasonography was unremarkable, whereas magnetic resonance imaging showed 2 intramuscular fluid collections requiring surgically drainage.
CONCLUSION
A review of medical literature showed that pyomyositis is an infrequent complication in children with hematological malignancies, and most cases are due to Staphylococcus aureus, whereas Pseudomonas aeruginosa appears to be rarely involved.
背景
我们报告了一例 11 岁女孩的病例，她最近被诊断为普通 B 细胞急性淋巴细胞白血病，在与化疗诱导期相关的严重中性粒细胞减少症期间出现左下肢绿脓杆菌肌炎。
观察结果
表现出的症状包括发热、腿部疼痛和拒绝行走。腘窝膝关节超声检查未见异常，而磁共振成像显示 2 处需要手术引流的肌肉内积液。
结论
对医学文献的回顾表明，肌炎是血液系统恶性肿瘤儿童的一种罕见并发症，大多数病例是由金黄色葡萄球菌引起的，而绿脓杆菌似乎很少涉及。
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