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隐源性卒中与瓣膜条索

Cryptogenic Stroke and Valvular Strands.

作者信息

Figueiredo Cátia, Rebelo Carla Sofia, Lemos Joana

机构信息

Department of Internal Medicine, Centro Hospitalar Tondela-Viseu, Viseu, Portugal.

出版信息

Eur J Case Rep Intern Med. 2020 Oct 20;7(12):001928. doi: 10.12890/2020_001928. eCollection 2020.

Abstract

BACKGROUND

Ischaemic stroke can be classified according to its aetiology. In cryptogenic stroke, Lambl's excrescences should be considered since they can only be detected through transesophageal echocardiography (TEE), which is not routinely performed.

CASE DESCRIPTION

The authors report the case of a 63-year-old Caucasian man with two ischaemic cerebral events associated with the presence of Lambl's excrescences in the aortic valve detected with TEE. Switching antiaggregant therapy to anticoagulant therapy allowed the patient to remain asymptomatic throughout a 3-year follow-up.

CONCLUSION

The lack of protocols for the management of cryptogenic stroke results in a delay in the identification of less frequent causes of stroke, leading to recurrent vascular events, morbidity and loss of functionality. The authors describe a patient who experienced multiple cerebral ischaemic events until the correct diagnosis was made.

LEARNING POINTS

Lambl's excrescences are a considered a rare cause of embolic stroke, probably because they are underdiagnosed.The pathophysiology is not fully understood, making therapeutic decisions difficult.Early recognition and management of this structural valve disease can prevent life-threatening complications.

摘要

背景

缺血性中风可根据其病因进行分类。在隐源性中风中,应考虑兰勃赘生物,因为它们只能通过经食管超声心动图(TEE)检测到,而TEE并非常规检查项目。

病例描述

作者报告了一例63岁的白种男性病例,该患者发生了两次缺血性脑事件,经TEE检测发现主动脉瓣存在兰勃赘生物。将抗血小板治疗转换为抗凝治疗后,患者在3年的随访中一直保持无症状。

结论

缺乏隐源性中风的管理方案导致识别中风罕见病因的延迟,从而导致复发性血管事件、发病率和功能丧失。作者描述了一名患者,在做出正确诊断之前经历了多次脑缺血事件。

经验教训

兰勃赘生物被认为是栓塞性中风的罕见病因,可能是因为它们诊断不足。其病理生理学尚未完全了解,这使得治疗决策困难。早期识别和管理这种结构性瓣膜疾病可以预防危及生命的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf41/7727622/07da282ae8e0/1928_Fig1.jpg

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