Katerndahl D A, Cohen P A
Department of Family Practice, University of Texas Health Science Center, San Antonio 78284.
Fam Pract Res J. 1987 Spring;6(3):123-9.
Meta-analysis has evolved as an alternative to the conventional narrative review. Its purpose is to statistically analyze a large collection of results from multiple studies in order to integrate the findings. There are three basic components of meta-analytic methodology. Inclusiveness involves the location of studies and decisions regarding which studies to include in the analysis. Quantification refers to the expression of such outcomes as effect sizes and the coding of study characteristics. Integrating outcomes involves the pooling of results from individual studies. Critics of meta-analysis have focused on aspects of the methodology, but careful meta-analytic procedure protects against most potential biases. The methodological and statistical rigor of meta-analysis pressures us to conceptualize our research more clearly and report results more completely.
荟萃分析已发展成为传统叙述性综述的替代方法。其目的是对来自多项研究的大量结果进行统计分析,以便整合研究结果。荟萃分析方法有三个基本组成部分。纳入性涉及研究的查找以及关于哪些研究纳入分析的决策。量化是指将效应大小等结果进行表达以及对研究特征进行编码。整合结果涉及汇总各个研究的结果。荟萃分析的批评者关注该方法的各个方面,但仔细的荟萃分析程序可防范大多数潜在偏差。荟萃分析在方法和统计方面的严谨性促使我们更清晰地构思我们的研究并更完整地报告结果。