Edwards M S, Prados M
Department of Neurological Surgery, School of Medicine, University of California, San Francisco.
Pediatr Neurosci. 1987;13(6):309-15. doi: 10.1159/000120349.
Brain stem gliomas constitute 10-20% of central nervous system tumors in children. Management of these tumors remains controversial. In general, the prognosis for long-term survival is poor, but brain stem gliomas represent a heterogeneous population of tumors, some of which have a better prognosis than others. Improvements in diagnostic imaging techniques, particularly the availability of magnetic resonance imaging, provide the means to differentiate among these populations. Advances in radiation therapy may provide the means to improve survival. In this article we review the reported series and the present state of the art for the diagnosis and management of children with brain stem gliomas.
脑干胶质瘤占儿童中枢神经系统肿瘤的10%-20%。这些肿瘤的治疗仍存在争议。总体而言,长期生存预后较差,但脑干胶质瘤是一组异质性肿瘤,其中一些的预后比其他的要好。诊断成像技术的进步,尤其是磁共振成像的应用,为区分这些肿瘤群体提供了手段。放射治疗的进展可能为提高生存率提供方法。在本文中,我们回顾了已报道的系列研究以及儿童脑干胶质瘤诊断和治疗的当前技术水平。