Departamento de Psiquiatría, Universidad Tecnológica de Pereira, Colombia; Grupo de Investigación Psiquiatría, Neurociencia y Comunidad, Universidad Tecnológica de Pereira, Colombia.
Departamento de Psiquiatría, Universidad Tecnológica de Pereira, Colombia; Grupo de Investigación Psiquiatría, Neurociencia y Comunidad, Universidad Tecnológica de Pereira, Colombia.
Rev Colomb Psiquiatr (Engl Ed). 2020 Oct-Dec;49(4):289-292. doi: 10.1016/j.rcp.2019.06.003. Epub 2019 Aug 27.
Leukoencephalopathy is a myelin disorder caused by multiple agents, including substance abuse.
A 28-year-old man arrived at the emergency department having suffered from asthenia, dizziness, disorientation and ataxia for two months. He had a two-year history of heroin inhalation. He arrived in a normal physical condition. Brain magnetic resonance showed bilateral diffuse hypointense lesions in the white matter. At day 3 after admission, he presented neurological deterioration, stupor, haemodynamic instability, respiratory failure, and died.
Toxic leukoencephalopathy symptoms start with inattention, memory and personality changes, and may eventually cause dementia and death. Heroin inhalation is a common practice and can lead to leukoencephalopathy.
Leukoencephalopathy associated with heroin inhalation is a rare entity that mainly affects young adults and has a high social impact. Its aetiology is unclear, it has no effective treatment and there is a high mortality rate. Heroin consumption is on the rise in Colombia, so TL should be considered by medical staff.
白质脑病是一种由多种物质引起的髓鞘疾病，包括物质滥用。
一名 28 岁男子因乏力、头晕、定向障碍和共济失调两个月而到急诊科就诊。他有两年海洛因吸入史。他入院时身体状况正常。脑部磁共振显示双侧脑白质弥漫性低信号病变。入院后第 3 天，他出现神经功能恶化、昏迷、血流动力学不稳定、呼吸衰竭，并死亡。
毒性白质脑病的症状首先表现为注意力不集中、记忆力和人格改变，最终可能导致痴呆和死亡。海洛因吸入是一种常见的做法，可能导致白质脑病。
与海洛因吸入相关的白质脑病是一种罕见的实体，主要影响年轻人，具有很高的社会影响。其病因尚不清楚，没有有效的治疗方法，死亡率很高。哥伦比亚的海洛因吸食量正在上升，因此医务人员应考虑到 TL。
Zotero 插件