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在资源匮乏的环境下,后矢状入路肛门直肠畸形修复术所面临的挑战、限制和失败:苏丹一家三级转诊中心的经验。

Challenges, constraints and failures that are related to the posterior sagittal anorectoplasty approach to anorectal malformations in a low-resource context: An experience from a sudanese tertiary referral centre.

机构信息

Department of Aging Science, Pediatric Surgery Unit, Civil Hospital 'Santo Spirito' of Pescara, University 'G. d'Annunzio' of Chieti-Pescara, Pescara, Italy.

Ada Manes Foundation for Children, Pescara, Italy.

出版信息

Afr J Paediatr Surg. 2020 Jul-Dec;17(3 & 4):79-84. doi: 10.4103/ajps.AJPS_16_20.

Abstract

BACKGROUND

Anorectal malformations (ARMs) in the sub-Saharan Africa are a common cause of neonatal referral for intestinal obstruction, and the posterior sagittal anorectoplasty (PSARP) approach is rapidly spreading. The small number of paediatric surgeons and the low-resource context limit children's access to care and constrain the quality of results. A retrospective, observational study has been done on a consecutive series of ARM cases admitted to a Sudanese tertiary paediatric surgical centre within the framework of a partnership between Italian and Sudanese academic institutions addressed to review and upgrade the standard of care of major congenital anomalies.

MATERIALS AND METHODS

The authors collected 94 ARM cases in a 3 years' period. Conditions on referral, operative procedures, post-operative course and follow-up were recorded and examined. Their correlations with complications and outcome were analysed.

RESULTS

The male/female ratio was 47/47. Eighty patients presented with an untreated ARM; 66 had a divided stoma and 14 had already a PSARP procedure, followed by a poor outcome or sequelae. In 25% of the cases, colostomy required re-doing. In 57 cases, a staged PSARP (primary or re-do) was done. Surgical-site infections occurred in nine patients. Some patients were lost to follow-up after preliminary colostomy. Post-operative dilatation programme suffered from the lack of systematic follow-up, and colostomy closure was possible in 46% of the cases due to problems in travelling and accessing hospital care. Anal stenosis was frequently observed among unfollowed patients.

CONCLUSION

Despite PSARP's widespread adoption in Africa, the risk of complications and failures is high. Primary management is often inappropriate, and a high rate of colostomy-related complications is observed. Poverty and lack of transportation reduce attendance to follow-up, hampering the final results. Investments in healthcare facilities and retention of trained health providers are needed to improve the standard of care.

摘要

背景

在撒哈拉以南非洲,肛门直肠畸形(ARM)是新生儿肠梗阻转诊的常见原因,后路纵切直肠肛门成形术(PSARP)方法正在迅速传播。儿童外科医生人数少,资源匮乏,限制了儿童获得护理的机会,并限制了治疗结果的质量。一项回顾性观察研究对在意大利和苏丹学术机构合作框架内,苏丹一家三级儿科外科中心连续收治的一系列 ARM 病例进行了研究,目的是审查和提高重大先天性畸形护理标准。

材料和方法

作者在 3 年期间收集了 94 例 ARM 病例。记录并检查了转诊时的情况、手术过程、术后过程和随访情况,并分析了它们与并发症和结果的关系。

结果

男女比例为 47/47。80 例患者表现为未治疗的 ARM;66 例患者行造口术,14 例患者已行 PSARP 术,但效果不佳或有后遗症。25%的病例需要重新行造口术。57 例患者行了分期 PSARP(初次或再次)手术。9 例患者发生手术部位感染。一些患者在初次造口术后失去随访。由于缺乏系统的随访,扩肛计划难以实施,只有 46%的患者能够进行造口关闭,因为他们在出行和获得医院护理方面存在问题。未随访患者中经常观察到肛门狭窄。

结论

尽管 PSARP 在非洲广泛采用,但并发症和失败的风险仍然很高。初次治疗通常不恰当,造口相关并发症发生率高。贫困和缺乏交通设施降低了随访率,影响了最终结果。需要投资医疗设施和留住受过培训的卫生工作者,以提高护理标准。

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