Brown Dominic, Tsampoukas Georgios
Urology Department, Princess Alexandra Hospital Trust, Harlow CM20 1QX, UK.
J Surg Case Rep. 2020 Jul 16;2020(7):rjaa241. doi: 10.1093/jscr/rjaa241. eCollection 2020 Jul.
Leydig cell tumours (LCTs) are rare testicular stromal neoplasms classically presenting with a painless testicular mass or swelling in adults. Symptoms secondary to hypogonadism may occur resulting from the hormonal activity of these tumours. Loss of libido is described in LCTs in conjunction with other symptoms; however, no case has reported this as the sole presenting feature. We describe the case of a 42-year-old man presenting to his General Practitioner with loss of libido and no other features suspicious of testicular cancer. Ultrasound performed due to an unrelated epididymal cyst detected an incidental mass confirmed as a benign LCT following radical orchidectomy. Biochemical markers remained normal throughout and following treatment his libido returned to normal. This case may serve as a reminder for clinicians to maintain a high index of suspicion for testicular neoplasms in patients with features of hypogonadism in the absence of classical features for testicular cancer.
睾丸间质细胞瘤(LCTs)是一种罕见的睾丸间质肿瘤,典型表现为成年男性无痛性睾丸肿块或肿胀。这些肿瘤的激素活性可能导致性腺功能减退继发的症状。在LCTs中,性欲减退常与其他症状同时出现;然而,尚无病例报告其为唯一的首发特征。我们报告一例42岁男性,因性欲减退就诊于全科医生,无其他可疑睾丸癌的特征。因无关的附睾囊肿进行超声检查时偶然发现一个肿块,根治性睾丸切除术后确诊为良性LCT。整个过程及治疗后生化指标均保持正常,其性欲也恢复正常。该病例提醒临床医生,对于缺乏睾丸癌典型特征但有性腺功能减退特征的患者,应高度怀疑睾丸肿瘤。