Nawalerspanya Siwanon, Sangmala Siripan, Aiempanakit Kumpol
Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.
Case Rep Dermatol. 2020 Nov 17;12(3):236-240. doi: 10.1159/000510737. eCollection 2020 Sep-Dec.
Leprosy or Hansen's disease is a chronic granulomatous infection that primarily affects the peripheral nerves and, consequently, the skin. Clinical manifestations vary from hypopigmentation to erythematous plaques, and it can present with leonine facies. We report a case of a patient with an uncommon clinical presentation of prurigo nodularis-like lesions without loss of sensation, for which two biopsy specimens demonstrated different histological subtypes. The first was the classic histology of lepromatous leprosy, whereas the other specimen revealed an atypical histoid leprosy variant pattern. This case report describes a patient with an atypical presentation of leprosy.
麻风病或汉森病是一种慢性肉芽肿性感染,主要影响周围神经,进而影响皮肤。临床表现从色素减退到红斑斑块不等,还可出现狮面。我们报告一例患者,其临床表现罕见,为类似结节性痒疹的皮损且无感觉丧失,两份活检标本显示出不同的组织学亚型。第一份是瘤型麻风的经典组织学表现,而另一份标本显示为非典型类脂质渐进性坏死型麻风变异模式。本病例报告描述了一名麻风病非典型表现的患者。