急性髓系白血病后发生血管免疫母细胞性T细胞淋巴瘤：推测的共同发病机制。一例病例报告及文献复习
Angioimmunoblastic T-cell lymphoma after acute myeloid leukemia: Alleged common pathogenesis. A case report and literature review.
作者信息
Iturrate Isabel, Loscertales Javier, Fernández-Ruiz Elena, Muñoz Patricia, López Consuelo, Del Campo Luciana, Muñoz Cecilia, Alegre Adrián
机构信息
Department of Hematology Universitary Hospital de La Princesa Madrid Spain.
Department of Molecular Biology Universitary Hospital de La Princesa Madrid Spain.
出版信息
Clin Case Rep. 2020 Nov 3;8(12):3494-3497. doi: 10.1002/ccr3.3430. eCollection 2020 Dec.
Abstract
The genomic landscape of AITL is characterized by mutation of epigenetic modifiers. This gene expression pattern resembles myeloid diseases and shows a potential role for hypomethylating agents as possible therapy for AITL.
摘要
血管免疫母细胞性T细胞淋巴瘤（AITL）的基因组特征是表观遗传修饰因子发生突变。这种基因表达模式类似于髓系疾病，并显示出低甲基化剂作为AITL可能治疗方法的潜在作用。
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