Gulistan Bahat, Istanbul University, Istanbul Medical School, Department of Internal Medicine, Capa, 34390, Istanbul, Turkey, Telephone: + 90 212 414 20 00-33204, Fax: + 90 212 532 42 08, E-mail address:
J Nutr Health Aging. 2021;25(1):13-17. doi: 10.1007/s12603-020-1544-8.
BACKGROUND/OBJECTIVE: While assessment of sarcopenia has drawn much attention, assessment of low muscle power has not been studied widely. This is, to a large extend, due to a more difficult assessment of power in practice. We aimed to compare the associations of low power and sarcopenia with functional and performance measures.
We designed a retrospective and cross-sectional study. Community-dwelling outpatient older adults applied to a university hospital between 2012 and 2020 composed the population. We estimated body composition by bioimpedance analysis. Other measures were handgrip strength, timed-up-and-go-test (TUG), usual gait speed (UGS), activities of daily living (ADL) and instrumental activities of daily living (IADL) tests. We assessed muscle power by a practical equation using a 5-repetition sit-to-stand power test. We adjusted the power by body weight and defined low muscle power threshold as the lowest sex-specific tertile. We noted demographic characteristics, number of medications, and diseases. We defined sarcopenia by EWGSOP2 definition.
Cut points for low relative muscle power were <2.684 and <1.962 W/kg in males and females, respectively. Low muscle power was related with both measures of disability (impaired ADL and IADL) (OR=2.4, 95% CI= 1.4-4.0, p=0.001; OR=2.4, 95% CI= 1.4-4.1, p=0.001; respectively). Low muscle strength (i.e. probable sarcopenia) was only related with disability in IADL (OR=3.6, 95% CI= 1.6-8.; p=0.002); confirmed sarcopenia was related with neither measures. Low muscle power was not related with impaired TUG (p=1) but with impaired UGS (OR=6.6, 95% CI= 3.6-11.0; p<0.001). Probable sarcopenia was not related with impaired TUG (p=0.08) but with impaired UGS (OR=2.4, 95% CI= 1.1-5.3; p=0.03) and confirmed sarcopenia was related with neither measures (p=1, p=0.3; respectively).
Low muscle power detected by simple and practically applicable CSST (Chair Sit To-Stand Test) power test was a convenient measure associated with functional and performance measures. It was related to functionality and performance measures more than sarcopenia. Future longitudinal studies are needed to examine whether it predicts future impairment in ADL, IADL, and performance measures.
背景/目的：虽然人们对肌少症的评估给予了极大关注，但对低肌肉力量的评估尚未得到广泛研究。这在很大程度上是因为在实践中更难以评估力量。我们旨在比较低力量和肌少症与功能和表现测量的相关性。
我们设计了一项回顾性和横断面研究。2012 年至 2020 年间，社区门诊老年患者到大学医院就诊，构成了研究人群。我们通过生物阻抗分析估计身体成分。其他测量包括握力、计时起立行走测试（TUG）、常规步行速度（UGS）、日常生活活动（ADL）和工具性日常生活活动（IADL）测试。我们使用 5 次重复坐站力量测试的实用方程评估肌肉力量。我们通过体重对力量进行了调整，并将最低的性别特异性三分位数定义为低肌肉力量阈值。我们记录了人口统计学特征、用药数量和疾病。我们按照 EWGSOP2 定义定义了肌少症。
男性和女性的低相对肌肉力量切点分别为<2.684 和<1.962 W/kg。低肌肉力量与残疾的两种测量指标（ADL 受损和 IADL 受损）均相关（OR=2.4，95%CI=1.4-4.0，p=0.001；OR=2.4，95%CI=1.4-4.1，p=0.001；分别）。低肌肉力量（即可能的肌少症）仅与 IADL 的残疾相关（OR=3.6，95%CI=1.6-8.0；p=0.002）；确诊的肌少症与这两种测量指标均无关。低肌肉力量与 TUG 受损无关（p=1），但与 UGS 受损相关（OR=6.6，95%CI=3.6-11.0；p<0.001）。可能的肌少症与 TUG 受损无关（p=0.08），但与 UGS 受损相关（OR=2.4，95%CI=1.1-5.3；p=0.03），而确诊的肌少症与这两种测量指标均无关（p=1，p=0.3；分别）。
通过简单实用的 CSST（坐站测试）力量测试检测到的低肌肉力量是一种方便的测量指标，与功能和表现测量指标相关。它与功能和表现测量指标的相关性大于肌少症。需要进行未来的纵向研究，以检验它是否能预测 ADL、IADL 和表现测量指标的未来受损。
