School of Medical Science, University of Campinas, Campinas, Brazil.
Autoimmunity Lab, School of Medical Science, University of Campinas, Campinas, Brazil.
Expert Rev Clin Immunol. 2021 Feb;17(2):155-161. doi: 10.1080/1744666X.2020.1865157. Epub 2021 Jan 22.
: Juvenile idiopathic arthritis (JIA) is the most common rheumatic inflammatory condition in childhood. The long-term morbidity, mortality, and quality of life have improved with the earlier use of disease-modifying drugs (DMARDs) and the availability of biology disease-modifying drugs (bDMARDs). Despite the improvement of treatment, around 50% of the patients reach adulthood with articular and/or extra articular disease activity. A careful planned transition from pediatric to adult care is necessary to reduce the loss of follow-up that is associated with stopping medications, flares, and disability due to untreated arthritis or uveitis.: This narrative review provides an overview of the importance of transition in JIA Articles were selected from Pubmed searches.: JIA patients, family, and healthcare workers have to be trained to provide an effective transition plan, based on local and national policies. Important aspects such as expectations, maturation, disease characteristics, disease activity, adherence, disability, and psychological aspects among others have to be considered and addressed during the transition phase to improve self-esteem, self-assurance, and quality of life.
幼年特发性关节炎(JIA)是儿童期最常见的风湿性炎症性疾病。随着疾病修饰药物(DMARDs)的更早使用和生物疾病修饰药物(bDMARDs)的出现,长期发病率、死亡率和生活质量都得到了改善。尽管治疗有所改善,但仍有 50%左右的患者成年后仍有关节和/或关节外疾病活动。为了减少因停止用药、发作和未治疗的关节炎或葡萄膜炎导致的残疾而导致的随访丢失,有必要从儿科向成人护理进行仔细的计划过渡。本综述文章概述了 JIA 过渡的重要性。文章是从 Pubmed 搜索中选择的。JIA 患者、家属和医疗保健工作者必须接受培训,根据当地和国家政策制定有效的过渡计划。在过渡阶段,必须考虑和解决预期、成熟度、疾病特征、疾病活动、依从性、残疾和心理等重要方面,以提高自尊心、自信和生活质量。