当大环肽与促黑素细胞激素受体的晶体结构相遇时。
When Macrocyclic Peptides Meet the Crystal Structure of a Melanocortin Receptor.
作者信息
Grieco Paolo
机构信息
Department of Pharmacy, University of Naples Federico II, CIRPEB, Centro Interuniversitario di Ricerca sui Peptidi Bioattivi, Via D. Montesano, 49, 80131 Naples, Italy.
出版信息
J Med Chem. 2021 Jan 14;64(1):354-356. doi: 10.1021/acs.jmedchem.0c02087. Epub 2021 Jan 4.
Abstract
This work reveals some key factors for the design of a novel generation of selective melanocortin ligands at the MC4 receptor.
摘要
这项研究揭示了设计新一代MC4受体选择性黑皮质素配体的一些关键因素。
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