Fabian T C, Mangiante E C, Patterson C R, Payne L W, Isaacson M L
Department of Surgery, University of Tennessee, Memphis 38163.
J Trauma. 1988 Jan;28(1):50-7. doi: 10.1097/00005373-198801000-00007.
The incidence, diagnosis, and impact on surgical management of myocardial contusion (MC) are incompletely defined. During a 12-month period, all patients admitted to a Level I trauma center with blunt trauma were prospectively evaluated for MC (n = 1,110). Those with anterior chest wall contusions, sternal or anterior rib fractures, or pain/tenderness of the anterior chest (n = 140, 13%) underwent immediate and daily ECG, and CPK isoenzymes were measured at admission and every 6 hours in the first 24 hours. Eighty-nine of these patients underwent gated ventricular angiography (GVA) and 66 underwent two-dimensional echocardiography (2D ECHO). MC was considered present if either: 1) CPK-MB was greater than or equal to 5% of total CPK, or 2) an abnormal admission ECG reverted to normal before patient discharge. Fifty-six patients (5% of admissions, 40% of those with apparent chest trauma) were positive by one or both criteria. Thirty patients (54%) were positive by CPK alone, 23 (41%) by both CPK and ECG, and three (5%) by ECG alone. Of the 53 with elevated CPK-MB, 14 (26%) were normal on admission with the remainder becoming elevated in the first 24 hours. 2D ECHO was abnormal in only three of 21 positive patients (14%), and GVA was abnormal in only three of 40 positive patients (7%). Surgical procedures requiring general anesthesia were performed in 37 (66%) of the positive patients. No significant arrhythmias developed under general anesthesia.
心肌挫伤(MC)的发病率、诊断及其对外科治疗的影响尚未完全明确。在12个月期间,对一家一级创伤中心收治的所有钝性创伤患者进行了心肌挫伤的前瞻性评估(n = 1110)。那些有前胸壁挫伤、胸骨或前肋骨骨折或前胸疼痛/压痛的患者(n = 140,占13%)立即接受每日心电图检查,并在入院时及最初24小时内每6小时检测一次肌酸磷酸激酶(CPK)同工酶。其中89例患者接受了门控心室造影(GVA),66例患者接受了二维超声心动图(2D ECHO)检查。如果出现以下情况之一,则认为存在心肌挫伤:1)CPK-MB大于或等于总CPK的5%,或2)异常的入院心电图在患者出院前恢复正常。56例患者(占入院患者的5%,占明显胸部创伤患者的40%)符合一项或两项标准呈阳性。30例患者(54%)仅CPK呈阳性,23例(41%)CPK和心电图均呈阳性,3例(5%)仅心电图呈阳性。在53例CPK-MB升高的患者中,14例(26%)入院时正常,其余患者在最初24小时内升高。21例阳性患者中只有3例(14%)二维超声心动图异常,40例阳性患者中只有3例(7%)门控心室造影异常。37例(66%)阳性患者接受了需要全身麻醉的外科手术。全身麻醉下未出现明显心律失常。