一项使用放射立体分析比较骨水泥型和非骨水泥型牛津单髁膝关节置换术的随机对照试验的五年结果。

Five-year results of a randomised controlled trial comparing cemented and cementless Oxford unicompartmental knee replacement using radiostereometric analysis.

作者信息

Campi S, Kendrick B J L, Kaptein B L, Valstar E R, Jackson W F M, Dodd C A F, Price A J, Murray D W

机构信息

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK.

Nuffield Orthopaedic Centre, NHS Foundation Trust, Oxford, UK.

出版信息

Knee. 2021 Jan;28:383-390. doi: 10.1016/j.knee.2020.09.003. Epub 2021 Jan 4.

Abstract

BACKGROUND

Cementless fixation is an alternative to cemented unicompartmental knee replacement (UKR). The aim of this study was to determine if cementless UKR fixation is as good as cemented by comparing the five-year migration measured radiostereometric analysis (RSA) in a randomised controlled trial.

METHODS

Thirty-nine patients were randomised to receive either a cemented or a cementless Oxford UKR and were studied at intervals up to five years to assess migration with RSA and radiolucencies with radiographs.

RESULTS

During the first year there was a small and significant amount of migration, predominantly in an anterior direction, of both the cemented (0.24 mm, SD 0.32, p = 0.01) and cementless (0.26 mm, SD 0.31, p = 0.00) femoral components. Thereafter there was no significant migration in any direction. At no stage was there any significant difference between the migrations of the cemented or cementless femoral components. During the first year, particularly the first three months, the cementless tibial components subsided 0.28 mm (SD 0.19, p = 0.00). This was significantly (p = 0.00) greater than the subsidence of the cemented tibial component (0.09, SD 0.19, p = 0.28). Between the second and fifth years there was no significant migration of either cemented or cementless tibial components. At five years radiolucent lines occurred significantly less with cementless (one partial) compared to cemented (six partial and one complete) tibial components.

CONCLUSIONS

As, between two and five years, there was no significant migration of cemented or cementless components, and no significant difference between them, we conclude that cementless fixation is as reliable as cemented. It may be better as there are fewer radiolucent lines.

摘要

背景

非骨水泥固定是骨水泥单髁膝关节置换术(UKR)的一种替代方法。本研究的目的是通过在一项随机对照试验中比较采用放射立体测量分析(RSA)测量的五年期移位情况,来确定非骨水泥UKR固定是否与骨水泥固定一样好。

方法

39例患者被随机分配接受骨水泥型或非骨水泥型牛津UKR,并在长达五年的时间里定期进行研究,以通过RSA评估移位情况,并通过X线片评估透亮线情况。

结果

在第一年,骨水泥型(0.24mm,标准差0.32,p = 0.01)和非骨水泥型(0.26mm,标准差0.31,p = 0.00)股骨组件均有少量且显著的移位,主要是向前移位。此后,在任何方向上均无显著移位。在任何阶段,骨水泥型或非骨水泥型股骨组件的移位之间均无显著差异。在第一年,尤其是前三个月,非骨水泥型胫骨组件下沉了0.28mm(标准差0.19,p = 0.00)。这显著(p = 0.00)大于骨水泥型胫骨组件的下沉(0.09,标准差0.19,p = 0.28)。在第二年至第五年期间,骨水泥型和非骨水泥型胫骨组件均无显著移位。在五年时,与骨水泥型(六个部分和一个完全透亮线)胫骨组件相比,非骨水泥型(一个部分透亮线)胫骨组件出现的透亮线明显更少。

结论

由于在两年至五年之间,骨水泥型和非骨水泥型组件均无显著移位,且它们之间无显著差异,我们得出结论,非骨水泥固定与骨水泥固定一样可靠。由于透亮线更少,它可能更好。

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