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心脏“凤凰”——来自完全切除的心房黏液瘤的隐匿性颅内出血性转移瘤

Cardiac phoenix in the brain-occult intracranial hemorrhagic metastases from completely resected atrial myxoma.

作者信息

Ghodasara Sagar Amrutlal, Balasubramanian Rohit, Varadharajan Shriram, Shobhanaa P S

机构信息

Department of Neurosurgery, Kovai Medical Center and Hospitals, Coimbatore, Tamil Nadu, India.

Department of Neuro-Imaging and Stroke Interventions, Kovai Medical Center and Hospitals, Coimbatore, Tamil Nadu, India.

出版信息

Surg Neurol Int. 2020 Nov 11;11:383. doi: 10.25259/SNI_410_2020. eCollection 2020.

Abstract

BACKGROUND

Cardiac myxomas are sporadic in nature and can often recur with a frequency of 3%, especially in middle-aged women, and 22% of the cases account to a part of Carney complex. Complete surgical removal of the myxoma is usually curative. Recurrence has been related with partial surgical excision, multicentricity, and embolism of tumor fragments.

CASE DESCRIPTION

We report a case of a patient with single brain metastases due to tumor embolization, from a cardiac myxoma operated prior. This case is exclusive, as tumor embolization from atrial myxoma to the cerebral cortex can be possible, within a short duration. In our case, the patient was evaluated with a magnetic resonance imaging brain and a solitary hemorrhagic lesion in the eloquent cerebral cortex was observed. To determine the primary etiology, the diagnosis of probable metastases was thought of, and a thorough workup was planned. Surprisingly, no primary lesion was detected, and as a histological diagnosis was required, he underwent a navigation-guided excisional biopsy of lesion. The biopsy was indicative of a metastatic deposit from an atrial myxoma.

CONCLUSION

In eloquent cortex lesions, gross total resection is challenging for a neurosurgeon especially when the patient has no significant neurological deficits. Timely gross total resection of a solitary metastatic lesion can improve the patient's outcome and can enhance early recovery with less or no morbidity.

摘要

背景

心脏黏液瘤本质上是散发性的,常以3%的频率复发,尤其在中年女性中,并且22%的病例属于卡尼综合征的一部分。黏液瘤的完整手术切除通常可治愈。复发与手术部分切除、多中心性以及肿瘤碎片栓塞有关。

病例描述

我们报告一例患者,因先前手术的心脏黏液瘤发生肿瘤栓塞导致单发脑转移。该病例较为独特,因为心房黏液瘤在短时间内有可能栓塞至大脑皮质。在我们的病例中,患者接受了脑部磁共振成像检查,发现优势大脑皮质有一个孤立的出血性病变。为确定原发性病因,考虑了可能的转移瘤诊断,并计划进行全面检查。令人惊讶的是,未检测到原发性病变,由于需要组织学诊断,患者接受了导航引导下的病变切除活检。活检结果显示为心房黏液瘤的转移灶。

结论

对于优势皮质病变,尤其是患者没有明显神经功能缺损时,神经外科医生进行全切除具有挑战性。及时全切除孤立的转移瘤可改善患者预后,并能促进早期恢复,减少或不出现并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/370b/7771508/dfbe3794faa9/SNI-11-383-g001.jpg

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