Raja Saadia Y, Ghori Uzma, Naqvi Haider Ali, Aijaz Sadaf, Anwar Adnan, Hashmi Atif A
Internal Medicine, Ziauddin University, Karachi, PAK.
Psychiatry, Ziauddin University, Karachi, PAK.
Cureus. 2020 Dec 2;12(12):e11861. doi: 10.7759/cureus.11861.
Objective This study aimed to evaluate different factors of social stressors among people with type II diabetes versus non-diabetics by using the Hamilton Depression Rating Scale (HAM-D). Methodology This case-control study was done for one year at Ziauddin University Hospital, Karachi, Pakistan. Diagnosed patients with type II diabetes between 25 and 60 years were included as cases and age-related healthy individuals as controls. Participants on any psychotropic medications, neurodegenerative disorders, or on chemotherapy were excluded. Hamilton Rating Scale for Depression (HRDS-17) was used for recording depressive symptoms. The Statistical Package for the Social Sciences (SPSS) version 26.0 (IBM Corp., Armonk, NY) was used for data analysis. The frequency was calculated for descriptive statistics and depression scores (HRDS-17). A significance level of 0.05 was considered. Results A total of 272 patients were divided into two groups, with 136 patients in the group with diabetes and 136 participants in the control group. The mean age among people with diabetes was 55.13±9.10 years and among non-diabetics was 43.25±12.97 years (p<0.001). The mean duration of illness in people with diabetes was 8.51±7.57 years and in non-diabetics, it was 6.73±4.42 years (p=0.018). The mean social rating in people with diabetes was 164.0±155.60 and in non-diabetics, it was 124.75±99.02 (p=0.014). Insomnia, both in the early and middle part of the night affecting work activities, hypochondriasis, and loss of weight, was significantly present among diabetics as compared to controls (p<0.05). Conclusion Most diabetics reported a significant effect on the quality of life based on social rating and health-care expenditure. They experienced depressive symptoms more frequently than non-diabetics. Insomnia in the middle of the night affected work and activities; hypochondriasis and weight loss were found to be substantially higher among patients with diabetes than in controls.
目的 本研究旨在通过使用汉密尔顿抑郁量表(HAM-D)评估2型糖尿病患者与非糖尿病患者社会压力源的不同因素。方法 本病例对照研究在巴基斯坦卡拉奇的齐亚乌丁大学医院进行了一年。纳入25至60岁的确诊2型糖尿病患者作为病例,年龄匹配的健康个体作为对照。排除正在服用任何精神药物、患有神经退行性疾病或正在接受化疗的参与者。使用汉密尔顿抑郁量表(HRDS-17)记录抑郁症状。使用社会科学统计软件包(SPSS)26.0版(IBM公司,纽约州阿蒙克)进行数据分析。计算频率用于描述性统计和抑郁评分(HRDS-17)。显著性水平设定为0.05。结果 总共272名患者分为两组,糖尿病组136例患者,对照组136名参与者。糖尿病患者的平均年龄为55.13±9.10岁,非糖尿病患者为43.25±12.97岁(p<0.001)。糖尿病患者的平均病程为8.51±7.57年,非糖尿病患者为6.73±4.42年(p=0.018)。糖尿病患者的平均社会评分是164.0±155.60,非糖尿病患者为124.75±99.02(p=0.014)。与对照组相比,糖尿病患者中存在显著的失眠(影响夜间早期和中期的工作活动)、疑病症和体重减轻(p<0.05)。结论 大多数糖尿病患者报告称,基于社会评分和医疗保健支出,生活质量受到显著影响。他们比非糖尿病患者更频繁地出现抑郁症状。半夜失眠影响工作和活动;糖尿病患者中的疑病症和体重减轻明显高于对照组。