[Tissue adhesion using highly-concentrated human fibrinogen on the example of free, autologe skin-grafting (author's transl)].

A report is given about the clinical experiences, made with a biological adhesive-system, consisting in thrombin, native human fibrinogen and clotting factor XIII. We used this adhesive-system in 28 cases of free skin-grafts, without any other kinds of skin-fixation. The highly adhesive properties, the good tissue compatibility recommend this system for using in free skin grafting. Possibilities for use in other kinds of operations in O.R.L. are discussed.