[两例慢性丙型肝炎再治疗的病例报告]
[Two case reports of chronic hepatitis C retreatment].
作者信息
Rožnovský Luděk, Mrázek Jakub, Petroušová Lenka, Orságová Irena, Kabieszová Libuše, Konečná Michaela, Kloudová Alena
机构信息
Department of Infectious Diseases, Faculty Hospital Ostrava, Czech Republic, e-mail:
出版信息
Klin Mikrobiol Infekc Lek. 2020 Sep;26(3):96-98.
In a group of 211 patients with chronic hepatitis C treated with direct-acting antivirals, four experienced therapy failure. Two patients, one originally treated with dasabuvir/ombitasvir/paritaprevir/ritonavir and the other with glecaprevir/pibrentasvir, received a triple combination of sofosbuvir, velpatasvir and voxilaprevir for 12 weeks. Following the retreatment, both patients were permanently virus-free.
在一组接受直接作用抗病毒药物治疗的211例慢性丙型肝炎患者中，有4例治疗失败。两名患者，一名最初接受达沙布韦/奥比他韦/帕利瑞韦/利托那韦治疗，另一名接受格卡瑞韦/哌仑他韦治疗，接受了索磷布韦、维帕他韦和伏西瑞韦的三联组合治疗12周。再次治疗后，两名患者均实现了持续病毒学应答。
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