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骨盆截肢后的软组织重建:游离腓肠肌皮瓣重建的疗效和可靠性。

Soft tissue reconstruction after pelvic amputation: The efficacy and reliability of free fillet flap reconstruction.

机构信息

Department of Musculoskeletal Surgery and Diseases, Tampere University Hospital and University of Tampere, Faculty of Medicine and Life Sciences Tampere, Finland.

Helsinki University Hospital, Department of Orthopaedics, Finland; University of Helsinki, Helsinki, Finland.

出版信息

J Plast Reconstr Aesthet Surg. 2021 May;74(5):987-994. doi: 10.1016/j.bjps.2020.10.070. Epub 2020 Nov 8.

Abstract

BACKGROUND

The majority of hindquarter amputation defects can be reconstructed with local anterior or posterior thigh flaps. Less than 5% of soft tissue defects require free flap reconstruction after tumour resection. Lower extremity fillet flap is described for reconstructing such defects, but the majority of publications are case reports or short single institutional series. There is a lack of data regarding the oncological outcomes of this highly selected patient group.

METHODS

Three tertiary sarcoma units treated twelve patients with hindquarter amputation or hip disarticulation for oncological indications with a free flap reconstruction of the soft tissue defect.

RESULTS

The median age of patients was 60 (range 12-76) years. Bone resection was carried out through the SI-joint in six patients and through the sacrum in five patients, with one patient undergoing hip disarticulation. Nine patients had R0 resection margin and three had R1 resection. The median surgical time and flap ischaemia time was 420 (249-650) and 89 (64-210) min, respectively. Median hospital and ICU stay was 18 (10-42) and 3 (1-8) days, respectively. Median blood loss was 2400 (950-10000) ml. There were three returns to theatre due to vascular compromise, with one total flap loss due to arterial thrombosis. Overall survival was 58% (95%CI 28-91%) both at 1-year and at 3-years.

DISCUSSION

Carefully selected patients requiring hindquarter amputation with extensive soft tissue defect necessitating free flap reconstruction can be reconstructed with a lower extremity free fillet flap with low rate of local wound complications. Survival of these patients is similar to that in patients requiring less extensive resection.

摘要

背景

大多数后肢截肢缺陷可以通过局部前或后大腿皮瓣重建。不到 5%的软组织缺陷需要在肿瘤切除后进行游离皮瓣重建。下肢 Fillet 皮瓣用于重建此类缺陷,但大多数出版物都是病例报告或短期单一机构系列。对于这一高度选择的患者群体,缺乏关于肿瘤学结果的数据。

方法

三个三级肉瘤单位为 12 名患者治疗了 12 名患者,这些患者由于肿瘤学指征需要进行后肢截肢或髋关节离断,并进行软组织缺损的游离皮瓣重建。

结果

患者的中位年龄为 60 岁(范围 12-76 岁)。6 名患者通过骶髂关节进行骨切除,5 名患者通过骶骨进行骨切除,1 名患者进行髋关节离断。9 名患者有 R0 切缘,3 名患者有 R1 切缘。中位手术时间和皮瓣缺血时间分别为 420(249-650)和 89(64-210)分钟。中位住院和 ICU 住院时间分别为 18(10-42)和 3(1-8)天。中位出血量为 2400(950-10000)ml。由于血管并发症,有 3 例返回手术室,1 例因动脉血栓形成导致总皮瓣丢失。1 年和 3 年的总生存率分别为 58%(95%CI 28-91%)。

讨论

对于需要广泛软组织缺陷的后肢截肢且需要游离皮瓣重建的精心选择的患者,可以用下肢游离 Fillet 皮瓣进行重建,局部伤口并发症发生率低。这些患者的存活率与需要较少广泛切除的患者相似。

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