Jenkins D, Jakubovic H R
Faculty of Medicine, University of Toronto, Ontario, Canada.
J Am Acad Dermatol. 1988 Feb;18(2 Pt 2):419-22.
A 58-year-old man presented with a 4-year history of a slowly enlarging, hyperkeratotic plaque on his glans penis that was compatible with a clinical diagnosis of pseudoepitheliomatous, keratotic, micaceous balanitis. The lesion had been treated unsuccessfully on three occasions with superficial shave excisional biopsies. Complete surgical excision produced excellent cosmetic and functional results with no evidence of recurrence at 3- and 6-month follow-up. A diagnosis of verrucous carcinoma was made on histologic examination of the excised material. Pseudoepitheliomatous, keratotic, micaceous balanitis is a distinctive clinical entity that represents a histologic spectrum ranging from hypertrophic-hyperplastic penile dystrophy to verrucous carcinoma.
一名58岁男性，其阴茎龟头有一缓慢增大的角化过度斑块，病史4年，临床诊断为假上皮瘤样、角化性、云母状龟头炎。该病变曾3次接受浅表削除切除活检治疗，但均未成功。完整手术切除后获得了极佳的美容和功能效果，在3个月和6个月的随访中均无复发迹象。对切除组织进行组织学检查后诊断为疣状癌。假上皮瘤样、角化性、云母状龟头炎是一种独特的临床实体，代表了从肥厚性增生性阴茎营养不良到疣状癌的组织学谱系。
