Department of Anesthesiology & Department of Medicine - Critical Care Division, Centre hospitalier de l'Université de Montréal, 1000, rue St-Denis, Porte D04-5028, Montréal, Québec, H2X 3J4, Canada.
Carrefour de l'innovation et de l'évaluation en santé, Centre de recherche du CHUM, Montréal, Canada.
BMC Anesthesiol. 2021 Jan 12;21(1):15. doi: 10.1186/s12871-021-01233-9.
Data on postoperative outcomes of the COVID-19 patient population is limited. We described COVID-19 patients who underwent a surgery and the pandemic impact on surgical activities.
We conducted a multicenter cohort study between March 13 and June 192,020. We included all COVID-19 patients who underwent surgery in nine centres of the Province of Québec, the Canadian province most afflicted by the pandemic. We also included concomitant suspected COVID-19 (subsequently confirmed not to have COVID-19) patients and patients who had recovered from it. We collected data on baseline characteristics, postoperative complications and postoperative mortality. Our primary outcome was 30-day mortality. We also collected data on overall surgical activities during this first wave and during the same period in 2019.
We included 44 COVID-19 patients, 18 suspected patients, and 18 patients who had recovered from COVID-19 at time of surgery. Among the 44 COVID-19 patients, 31 surgeries (71%) were urgent and 16 (36%) were major. In these patients, pulmonary complications were frequent (25%) and 30-day mortality was high (15.9%). This mortality was higher in patients with symptoms (23.1%) compared to those without symptoms (5.6%), although not statistically significant (p = 0.118). Of the total 22,616 cases performed among participating centres during the study period, only 0.19% had COVID-19 at the time of surgery. Fewer procedures were performed during the study period compared to the same period in 2019 (44,486 cases).
In this Canadian cohort study, postoperative 30-day mortality in COVID-19 patients undergoing surgery was high (15.9%). Although few surgeries were performed on COVID-19 patients, the pandemic impact on surgical activity volume was important.
ClinicalTrials.gov Identifier: NCT04458337 .
关于 COVID-19 患者术后结果的数据有限。我们描述了接受手术的 COVID-19 患者以及大流行对手术活动的影响。
我们进行了一项 3 月 13 日至 6 月 19 日期间的多中心队列研究,纳入了魁北克省九个中心的所有 COVID-19 患者接受手术,魁北克省是加拿大受大流行影响最严重的省份。我们还纳入了同时患有疑似 COVID-19(随后证实没有 COVID-19)的患者和已康复的患者。我们收集了基线特征、术后并发症和术后死亡率的数据。我们的主要结局是 30 天死亡率。我们还收集了在此波疫情期间和 2019 年同期的整体手术活动数据。
我们纳入了 44 例 COVID-19 患者、18 例疑似患者和 18 例在手术时已从 COVID-19 中康复的患者。在 44 例 COVID-19 患者中,31 例手术(71%)为紧急手术,16 例(36%)为重大手术。这些患者中肺部并发症常见(25%),30 天死亡率高(15.9%)。有症状患者(23.1%)的死亡率高于无症状患者(5.6%),但无统计学意义(p=0.118)。在研究期间参与中心进行的 22616 例手术中,只有 0.19%的手术时有 COVID-19。与 2019 年同期相比,研究期间的手术量减少(44486 例)。
在这项加拿大队列研究中,COVID-19 患者术后 30 天死亡率较高(15.9%)。尽管对 COVID-19 患者进行的手术很少,但大流行对手术活动量的影响很大。
ClinicalTrials.gov 标识符:NCT04458337。