Suppr超能文献

外科 COVID-19 患者的术后结局:一项多中心队列研究。

Postoperative outcomes in surgical COVID-19 patients: a multicenter cohort study.

机构信息

Department of Anesthesiology & Department of Medicine - Critical Care Division, Centre hospitalier de l'Université de Montréal, 1000, rue St-Denis, Porte D04-5028, Montréal, Québec, H2X 3J4, Canada.

Carrefour de l'innovation et de l'évaluation en santé, Centre de recherche du CHUM, Montréal, Canada.

出版信息

BMC Anesthesiol. 2021 Jan 12;21(1):15. doi: 10.1186/s12871-021-01233-9.

Abstract

BACKGROUND

Data on postoperative outcomes of the COVID-19 patient population is limited. We described COVID-19 patients who underwent a surgery and the pandemic impact on surgical activities.

METHODS

We conducted a multicenter cohort study between March 13 and June 192,020. We included all COVID-19 patients who underwent surgery in nine centres of the Province of Québec, the Canadian province most afflicted by the pandemic. We also included concomitant suspected COVID-19 (subsequently confirmed not to have COVID-19) patients and patients who had recovered from it. We collected data on baseline characteristics, postoperative complications and postoperative mortality. Our primary outcome was 30-day mortality. We also collected data on overall surgical activities during this first wave and during the same period in 2019.

RESULTS

We included 44 COVID-19 patients, 18 suspected patients, and 18 patients who had recovered from COVID-19 at time of surgery. Among the 44 COVID-19 patients, 31 surgeries (71%) were urgent and 16 (36%) were major. In these patients, pulmonary complications were frequent (25%) and 30-day mortality was high (15.9%). This mortality was higher in patients with symptoms (23.1%) compared to those without symptoms (5.6%), although not statistically significant (p = 0.118). Of the total 22,616 cases performed among participating centres during the study period, only 0.19% had COVID-19 at the time of surgery. Fewer procedures were performed during the study period compared to the same period in 2019 (44,486 cases).

CONCLUSION

In this Canadian cohort study, postoperative 30-day mortality in COVID-19 patients undergoing surgery was high (15.9%). Although few surgeries were performed on COVID-19 patients, the pandemic impact on surgical activity volume was important.

TRIAL REGISTRATION

ClinicalTrials.gov Identifier: NCT04458337 .

摘要

背景

关于 COVID-19 患者术后结果的数据有限。我们描述了接受手术的 COVID-19 患者以及大流行对手术活动的影响。

方法

我们进行了一项 3 月 13 日至 6 月 19 日期间的多中心队列研究,纳入了魁北克省九个中心的所有 COVID-19 患者接受手术,魁北克省是加拿大受大流行影响最严重的省份。我们还纳入了同时患有疑似 COVID-19(随后证实没有 COVID-19)的患者和已康复的患者。我们收集了基线特征、术后并发症和术后死亡率的数据。我们的主要结局是 30 天死亡率。我们还收集了在此波疫情期间和 2019 年同期的整体手术活动数据。

结果

我们纳入了 44 例 COVID-19 患者、18 例疑似患者和 18 例在手术时已从 COVID-19 中康复的患者。在 44 例 COVID-19 患者中,31 例手术(71%)为紧急手术,16 例(36%)为重大手术。这些患者中肺部并发症常见(25%),30 天死亡率高(15.9%)。有症状患者(23.1%)的死亡率高于无症状患者(5.6%),但无统计学意义(p=0.118)。在研究期间参与中心进行的 22616 例手术中,只有 0.19%的手术时有 COVID-19。与 2019 年同期相比,研究期间的手术量减少(44486 例)。

结论

在这项加拿大队列研究中,COVID-19 患者术后 30 天死亡率较高(15.9%)。尽管对 COVID-19 患者进行的手术很少,但大流行对手术活动量的影响很大。

试验注册

ClinicalTrials.gov 标识符:NCT04458337。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1312/7802235/275c8283c2d5/12871_2021_1233_Fig1_HTML.jpg

相似文献

1
Postoperative outcomes in surgical COVID-19 patients: a multicenter cohort study.
BMC Anesthesiol. 2021 Jan 12;21(1):15. doi: 10.1186/s12871-021-01233-9.
4
5
Impact of the COVID-19 Pandemic on the Outcomes of Patients Undergoing Oncological Surgeries: CORONAL Study.
Ann Surg Oncol. 2024 Jun;31(6):3639-3648. doi: 10.1245/s10434-024-15152-9. Epub 2024 Mar 26.
7
Performing gynecologic cancer surgery during the COVID-19 pandemic in Turkey: A multicenter retrospective observational study.
Int J Gynaecol Obstet. 2020 Oct;151(1):33-38. doi: 10.1002/ijgo.13296. Epub 2020 Aug 11.
8
IMPACT-Restart: the influence of COVID-19 on postoperative mortality and risk factors associated with SARS-CoV-2 infection after orthopaedic and trauma surgery.
Bone Joint J. 2020 Dec;102-B(12):1774-1781. doi: 10.1302/0301-620X.102B12.BJJ-2020-1395.R2. Epub 2020 Oct 21.

引用本文的文献

1
Perioperative outcomes in patients with symptomatic versus asymptomatic previous COVID-19 infection undergoing neurosurgical treatment (post-COVID-19 study).
J Anaesthesiol Clin Pharmacol. 2025 Jan-Mar;41(1):98-105. doi: 10.4103/joacp.joacp_313_23. Epub 2024 Dec 16.
2
Impact of COVID-19 on Thrombotic Complications in Microsurgery: Deep Inferior Epigastric Perforator Flap Outcomes Amid Pandemic.
Plast Reconstr Surg Glob Open. 2025 Feb 14;13(2):e6544. doi: 10.1097/GOX.0000000000006544. eCollection 2025 Feb.
6
Utilization of SARS-COV-2 positive donors and recipients for liver transplantation in the pandemic era - An evidence-based review.
J Liver Transpl. 2022 Jul-Sep;7:100081. doi: 10.1016/j.liver.2022.100081. Epub 2022 Mar 11.
7
Postoperative Outcomes After Emergency Surgery in COVID-19 Patients: An Ambispective Matched Cohort Study.
Cureus. 2024 Mar 9;16(3):e55845. doi: 10.7759/cureus.55845. eCollection 2024 Mar.
8
Postoperative Outcomes Associated with the Timing of Surgery After SARS-CoV-2 Infection.
Ann Surg. 2024 Aug 1;280(2):241-247. doi: 10.1097/SLA.0000000000006227. Epub 2024 Feb 7.
9
Outcomes of Patients Undergoing Major Surgery for Cancer with COVID-19 in the Postoperative Period.
Indian J Surg Oncol. 2023 Dec;14(4):876-880. doi: 10.1007/s13193-023-01797-7. Epub 2023 Jul 7.

本文引用的文献

2
Development and Performance of a Clinical Decision Support Tool to Inform Resource Utilization for Elective Operations.
JAMA Netw Open. 2020 Nov 2;3(11):e2023547. doi: 10.1001/jamanetworkopen.2020.23547.
4
Delaying surgery for patients with a previous SARS-CoV-2 infection.
Br J Surg. 2020 Nov;107(12):e601-e602. doi: 10.1002/bjs.12050. Epub 2020 Sep 25.
6
COVID-19 in Canada: Experience and Response.
JAMA. 2020 Aug 25;324(8):743-744. doi: 10.1001/jama.2020.14033.
8
Preoperative SARS-CoV-2 screening: Can it really rule out COVID-19?
Can J Anaesth. 2020 Oct;67(10):1321-1326. doi: 10.1007/s12630-020-01746-w. Epub 2020 Jun 23.
10
Guidelines: Anaesthesia in the context of COVID-19 pandemic.
Anaesth Crit Care Pain Med. 2020 Jun;39(3):395-415. doi: 10.1016/j.accpm.2020.05.012. Epub 2020 Jun 5.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验