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[氧对在不同pH值介质中辐照的核酸的γ辐射损伤的影响]

[Effect of oxygen on gamma-radiation damage to nucleic acids irradiated in media with different pH values].

作者信息

Sukhorukov B I, Rybalko L M, Shabarchina L I

出版信息

Radiobiologiia. 1988 Jan-Feb;28(1):23-7.

PMID:3344326
Abstract

The injury to DNA and RNA exposed to gamma-radiation in media of varying acidity with oxygen present or absent therein has been investigated. The interaction of the protonated base with a superoxide radical has been shown to contribute markedly to the oxygen effect of the radiation injury to nucleic acids.

摘要

研究了在有或无氧存在的不同酸度介质中,暴露于γ辐射下的DNA和RNA的损伤情况。已表明质子化碱基与超氧自由基的相互作用对核酸辐射损伤的氧效应有显著贡献。

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