肠道微生物组：在放射性损伤中，它是我们最好的亦敌亦友吗？

The Intestinal Microbiota: Our Best Frenemy in Radiation-Induced Damages?

机构信息

INSERM U1016, team ''Mucosal microbiota in chronic inflammatory diseases'', CNRS UMR 8104, Université de Paris, Paris, France.

出版信息

Cell Host Microbe. 2021 Jan 13;29(1):7-9. doi: 10.1016/j.chom.2020.12.013.

DOI:10.1016/j.chom.2020.12.013

PMID:33444556

Abstract

High-dose ionizing radiation used during cancer radiotherapy is associated with the induction of hematopoietic, gastrointestinal, and cerebrovascular injuries. In a recent Science issue, Guo et al. demonstrated that the gut microbiota-and its associated metabolites-play a central role in protecting against high-dose radiation.

摘要

高剂量电离辐射在癌症放射治疗中被应用，其与造血、胃肠道和脑血管损伤的诱导有关。在最近的一期《科学》杂志上，Guo 等人证明了肠道微生物群及其相关代谢物在预防高剂量辐射中起着核心作用。