轴向压缩对脊柱组织细胞和力学功能的影响；重点研究髓核和纤维环：综述。
The Influence of Axial Compression on the Cellular and Mechanical Function of Spinal Tissues; Emphasis on the Nucleus Pulposus and Annulus Fibrosus: A Review.
机构信息
Department of Kinesiology and Physical Education, Wilfrid Laurier University, 75 University Avenue West, Waterloo, ON N2 L 3C5.
Department of Kinesiology and Physical Education, Wilfrid Laurier University, 75 University Avenue West, Waterloo, ON N2 L 3C5; Department of Health Sciences, Wilfrid Laurier University, 75 University Avenue West, Waterloo, ON N2 L 3C5.
出版信息
J Biomech Eng. 2021 May 1;143(5). doi: 10.1115/1.4049749.
In light of the correlation between chronic back pain and intervertebral disc (IVD) degeneration, this literature review seeks to illustrate the importance of the hydraulic response across the nucleus pulposus (NP)-annulus fibrosus (AF) interface, by synthesizing current information regarding injurious biomechanics of the spine, stemming from axial compression. Damage to vertebrae, endplates (EPs), the NP, and the AF, can all arise from axial compression, depending on the segment's posture, the manner in which it is loaded, and the physiological state of tissue. Therefore, this movement pattern was selected to illustrate the importance of the bracing effect of a pressurized NP on the AF, and how injuries interrupting support to the AF may contribute to IVD degeneration.
鉴于慢性背痛与椎间盘（IVD）退变之间的相关性，本文献综述旨在通过综合有关轴向压缩引起的脊柱损伤生物力学的最新信息，说明核-纤维环（NP）界面水力反应的重要性。轴向压缩可导致椎体、终板（EP）、NP 和纤维环（AF）损伤，这取决于节段的姿势、加载方式和组织的生理状态。因此，选择这种运动模式来说明受压 NP 对 AF 的支撑作用的重要性，以及中断对 AF 的支撑如何导致 IVD 退变。
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