Corbo R M, Scacchi R, Mantuano E
Department of Genetics and Molecular Biology, La Sapienza University, Rome, Italy.
Enzyme. 1988;39(1):50-3. doi: 10.1159/000469093.
The effect of three thiol reagents on erythrocyte adenosine deaminase (ADA) activity has been studied. Oxidized glutathione and iodoacetate do not alter ADA activity, while the treatment with p-chloromercuribenzoate at similar concentrations results in a reduction of enzymatic activity which is statistically significant only for ADA 1, but not ADA 2-1 phenotype haemolysates.