Scottish Council on Human Bioethics, Edinburgh, Scotland.
New Bioeth. 2021 Mar;27(1):19-29. doi: 10.1080/20502877.2020.1869467. Epub 2021 Jan 17.
Human germline genome editing is increasingly being seen as acceptable provided certain conditions are satisfied. Accordingly, genetic modifications would take place on eggs or sperm (or their precursor cells) as well as very early embryos for the purpose of bringing children into existence with or without particular genetic traits. In this context, a number of already discussed and separate arguments, such as the (1) synecdoche, (2) non-identity (3) inherent equality and (4) expressivist arguments, can be brought together in the new context of examining, from an ethical perspective, some of the possible consequences of such germline genome editing. In so doing, it becomes clear that these novel procedures are incompatible with the concept of equality in value and in worth of all human beings in a genuinely inclusive society. Such equality is expressed in Article 1 of the United Nations' which states that: 'All human beings are born … equal in dignity and rights.'
人类生殖系基因组编辑越来越被视为可接受的，只要满足某些条件。因此，遗传修饰将发生在卵子或精子（或其前体细胞）以及非常早期的胚胎上，目的是将具有或不具有特定遗传特征的儿童带到这个世界上。在这种情况下，可以将已经讨论过的一些单独的论点，如（1）提喻法，（2）非同一性，（3）内在平等和（4）表现主义论点，结合起来，从伦理的角度来考察这种生殖系基因组编辑的一些可能后果。这样做可以清楚地表明，这些新程序与真正包容的社会中所有人类在价值和价值方面的平等概念是不相容的。这种平等在联合国第 1 条中得到了体现，该条规定：“所有人……在尊严和权利上一律平等。”
