Department of Surgical Sciences, University Hospital, Uppsala, Sweden.
Interv Neuroradiol. 2021 Jun;27(3):372-387. doi: 10.1177/1591019920988204. Epub 2021 Jan 20.
The aim of this study was to evaluate our results regarding treatment options, complications, and outcomes in patients with non-saccular aneurysms of cerebral arteries belonging to type 1 and type 4 according to Mizutani's classification.
A total of 26 aneurysms in 26 patients were treated between 2014 and 2019. There were 13 males (mean age 42.77 ± 11.73 years) and 13 females (mean age 50.84 ± 9.37 years). In 23 cases the onset was haemorrhagic and in three cases non-haemorrhagic. A combination of conventional stents and coils was used in 10 cases, conventional stents and flow diverters in three cases, flow diverters and coils in five cases, and flow diverters only were used in eight cases. Radiological results of treatment were assessed after eight months and clinical after one year.
In 24 patients, aneurysms were occluded at the end of the follow-up period. An iatrogenic dissection and two haemorrhagic complications were registered. In three cases, parent arteries were occluded due to re-growth of the aneurysm, which caused middle cerebral artery infarction in one case. A favourable clinical outcome was registered in 19, patients, and non-favourable in five. Two patients died in the early postoperative period due to extensive damage to the brain parenchyma caused by initial bleeding.
Our results indicate that treatment of type 1 and type 4 non-saccular aneurysms with various combination of stents and flow diverters, with or without coils, is promising, although very challenging and technically demanding.
本研究旨在评估我们在根据 Mizutani 分类属于 1 型和 4 型的非囊状脑动脉动脉瘤患者的治疗选择、并发症和结果方面的治疗结果。
2014 年至 2019 年间共治疗 26 例患者的 26 个动脉瘤。其中 13 例为男性(平均年龄 42.77±11.73 岁),13 例为女性(平均年龄 50.84±9.37 岁)。23 例首发症状为出血性,3 例为非出血性。10 例采用传统支架结合线圈,3 例采用传统支架结合血流导向装置,5 例采用血流导向装置结合线圈,8 例仅采用血流导向装置。术后 8 个月评估治疗的放射学结果,术后 1 年评估临床结果。
在 24 例患者中,在随访结束时动脉瘤闭塞。登记了 1 例医源性夹层和 2 例出血性并发症。在 3 例患者中,由于动脉瘤再生长导致载瘤动脉闭塞,其中 1 例导致大脑中动脉梗死。19 例患者的临床结果良好,5 例患者的临床结果不佳。由于初始出血导致脑实质广泛损伤,2 例患者在术后早期死亡。
我们的结果表明,使用各种支架和血流导向装置组合(有或无线圈)治疗 1 型和 4 型非囊状动脉瘤具有很大的前景,尽管非常具有挑战性和技术要求很高。