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孕期女性性功能会发生什么变化?

What happens to female sexual function during pregnancy?

作者信息

Cassis Charlotte, Mukhopadhyay Sambit, Morris Edward, Giarenis Ilias

机构信息

Norfolk and Norwich University Hospital, Colney Lane, Norwich, NR4 7UY, United Kingdom.

Norfolk and Norwich University Hospital, Colney Lane, Norwich, NR4 7UY, United Kingdom.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2021 Mar;258:265-268. doi: 10.1016/j.ejogrb.2021.01.003. Epub 2021 Jan 15.

DOI:10.1016/j.ejogrb.2021.01.003
PMID:33485263
Abstract

INTRODUCTION

Female sexual function remains an under-investigated and neglected topic in medical research. Studies have found a strong association between female sexual dysfunction (FSD) and decreased physical, emotional and overall life satisfaction [1]. Although FSD and the impact it has on quality of life is becoming increasingly recognised, the effect of pregnancy on FSD is relatively under-researched.

METHODS

Based on a significance level of 5% and a study power of 80 % a power calculation was performed using an assumed 20 % loss to follow up rate. 85 primiparous women with singleton pregnancies were recruited at their dating scan and asked to complete the Female Sexual Function Index (FSFI) questionnaire in each trimester. The total score and the six domains (pain, satisfaction, orgasm, desire, lubrication and desire) were compared with Friedman's ANOVA. The validated cut-off score of 26.55 was used to diagnose FSD.

RESULTS

There was an overall decrease in total FSFI scores across the three trimesters, from a median full-scale score of 27.5 in the first trimester, to 24.7 in the second and 21.4 in the third trimester. There was a very significant decrease in all scores (the full scale score and the six domains- desire, lubrication, arousal, orgasm, satisfaction and pain), from the first trimester to the third trimester with each outcome (p < 0.0001). There were 30 women with FDS in the first trimester, 50 in the second and 68 in the third (p < 0.05).

CONCLUSIONS

For primiparous women pregnancy appears to have a negative impact on sexual function with 86.1 % of women being classified as suffering from FSD in the third trimester. The importance of sexual function in overall quality life is well known and so it is important that the changes experienced by women and their partners are discussed by doctors with their patients.

摘要

引言

女性性功能在医学研究中仍是一个研究不足且被忽视的课题。研究发现女性性功能障碍(FSD)与身体、情感及总体生活满意度下降之间存在密切关联[1]。尽管FSD及其对生活质量的影响日益受到认可,但妊娠对FSD的影响相对研究较少。

方法

基于5%的显著性水平和80%的研究效能,使用假定20%的失访率进行效能计算。85名单胎初产妇在孕早期超声检查时被招募,并被要求在孕期的每个阶段完成女性性功能指数(FSFI)问卷。总得分及六个领域(疼痛、满意度、性高潮、性欲、润滑和唤起)通过Friedman方差分析进行比较。采用经过验证的26.55分的临界值来诊断FSD。

结果

在三个孕期中,FSFI总得分总体呈下降趋势,从孕早期的中位数全量表得分27.5分,降至孕中期的24.7分和孕晚期的21.4分。从孕早期到孕晚期,所有得分(全量表得分及六个领域——性欲、润滑、唤起、性高潮、满意度和疼痛)均有非常显著的下降(p < 0.0001)。孕早期有30名女性患有FSD,孕中期有50名,孕晚期有68名(p < 0.05)。

结论

对于初产妇而言,妊娠似乎对性功能有负面影响,在孕晚期86.1%的女性被归类为患有FSD。性功能在总体生活质量中的重要性是众所周知的,因此医生与患者讨论女性及其伴侣所经历的变化非常重要。

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