General Medicine, Fukuoka University Hospital, Fukuoka, Japan.
General Medicine, Fukuoka University Hospital, Fukuoka, Japan.
J Infect Chemother. 2021 Jun;27(6):902-905. doi: 10.1016/j.jiac.2021.01.001. Epub 2021 Jan 20.
Transient global amnesia (TGA) is an uncommon disease characterized by sudden onset anterograde amnesia that typically improves within 24 hours. A 35-year-old woman presented with complete disruption of memory that had started on the previous day. She had fever and heart murmur and was diagnosed as having infective endocarditis with Staphylococcus lugdunensis, a coagulase-negative staphylococcus. Septic embolizations were found in the spleen and kidney on CT scan. The patient underwent aortic valve replacement. MRI susceptibility-weighted imaging showed a dotted low intensity area in the right hippocampus. Recently, etiology of TGA is reported to be related to hippocampal disorder. We report a rare case of TGA with hippocampal infarction due to septic embolism from infective endocarditis.
短暂性全面遗忘症(TGA)是一种不常见的疾病,其特征为突然发作的顺行性遗忘症,通常在 24 小时内改善。一位 35 岁女性出现了完全记忆障碍,该障碍从前一天开始。她有发热和心脏杂音,并被诊断为感染性心内膜炎,病原体为凝固酶阴性葡萄球菌中的路邓葡萄球菌。CT 扫描发现脾脏和肾脏有脓毒性栓塞。患者接受了主动脉瓣置换术。MRI 磁敏感加权成像显示右海马有斑点状低信号区。最近,TGA 的病因被报道与海马紊乱有关。我们报告了一例因感染性心内膜炎引起的脓毒性栓塞导致海马梗死的 TGA 罕见病例。