干眼亚型之间眼痛严重程度的评估。

Evaluation of Eye-Pain Severity between Dry-Eye Subtypes.

作者信息

Yoshikawa Yamato, Yokoi Norihiko, Kato Hiroaki, Sakai Rieko, Komuro Aoi, Sonomura Yukiko, Ikeda Tsunehiko, Sotozono Chie

机构信息

Department of Ophthalmology, Osaka Medical College, Takatsuki-City, Osaka 569-8686, Japan.

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.

出版信息

Diagnostics (Basel). 2021 Jan 25;11(2):166. doi: 10.3390/diagnostics11020166.

DOI:10.3390/diagnostics11020166

PMID:33503963

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7911415/

Abstract

The aim of this study was to assess eye pain between dry eye (DE) subtypes using questionnaires and the PainVision (Osachi) apparatus. This study involved 52 eyes of 52 DE patients with eye pain (43 females and 9 males; mean age: 64.2 ± 13.2 (mean ± SD) years) who were classified into three DE subtypes (aqueous deficient DE (ADDE); decreased wettability DE (DWDE); and increased evaporation DE (IEDE)) based on fluorescein breakup pattern. In all subjects, severity of eye pain was evaluated using PainVision, the DE-symptom-questionnaire visual analog scale (DSQ-VAS), and the Short-Form McGill Pain Questionnaire 2 (SF-MPQ-2). The severity of eye pain was compared between the three DE subtypes. PainVision findings revealed greater severity of eye pain in ADDE and DWDE than in IEDE ( < 0.05, respectively), despite no difference being found in each questionnaire. A significant correlation was found between eye pain in DSQ-VAS and continuous pain, intermittent pain, neuropathic pain, and total pain in SF-MPQ-2 (R = 0.50, 0.49, 0.47, and 0.56, respectively) (all: < 0.001). Greater severity of eye pain was found in ADDE and DWDE than in IEDE, and PainVision was found useful for the objective assessment of eye pain.

摘要

本研究的目的是使用问卷和PainVision（Osachi）仪器评估干眼（DE）各亚型之间的眼痛情况。本研究纳入了52例有眼痛的DE患者的52只眼（43例女性和9例男性；平均年龄：64.2±13.2（平均值±标准差）岁），这些患者根据荧光素破裂模式被分为三种DE亚型（水液缺乏性DE（ADDE）；湿润性降低性DE（DWDE）；蒸发增加性DE（IEDE））。在所有受试者中，使用PainVision、干眼症状问卷视觉模拟量表（DSQ-VAS）和简化麦吉尔疼痛问卷2（SF-MPQ-2）评估眼痛的严重程度。比较三种DE亚型之间眼痛的严重程度。PainVision的结果显示，ADDE和DWDE的眼痛严重程度高于IEDE（分别为P<0.05），尽管各问卷中未发现差异。DSQ-VAS中的眼痛与SF-MPQ-2中的持续性疼痛、间歇性疼痛、神经性疼痛和总疼痛之间存在显著相关性（R分别为0.50、0.49、0.47和0.56）（均为P<0.001）。ADDE和DWDE的眼痛严重程度高于IEDE，并且发现PainVision有助于客观评估眼痛。