Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, 97331, USA.
Department of Chemistry, Oregon State University, Corvallis, OR, 97331, USA.
Anal Bioanal Chem. 2021 Mar;413(6):1651-1664. doi: 10.1007/s00216-020-03127-0. Epub 2021 Jan 28.
Parent and alkylated polycyclic aromatic hydrocarbons (PAHs) are present in a number of different sources in varying proportions depending on the source material and weathering. This range of PAH sources can make it difficult to determine the origin of exposure(s). Ratios of alkylated and parent PAHs have been applied as a forensic tool to distinguish between different sources. However, few studies have examined PAH ratios comprehensively as indicators for sourcing beyond a single study area or matrix type. In this paper, we introduce an expanded analytical method based on ASTM D7363-13a which we adapted for a gas chromatography triple quadrupole mass spectrometry instrument. The modifications increase selectivity and sensitivity compared to the ASTM method. We added five alkylated series to the method. This method has then been applied to 22 independent forensic ratios. We evaluated the method and the forensic ratios with certified reference materials and known environmental samples. This analytical method and thirteen PAH ratios were found to accurately predict sources of PAHs.
父母和烷基化多环芳烃（PAHs）存在于许多不同的来源中，其比例因来源材料和风化程度而异。这种范围广泛的 PAH 来源可能会使确定暴露源变得困难。烷基化和母体 PAH 的比例已被用作法医工具，以区分不同的来源。然而，很少有研究全面检查 PAH 比例作为单一研究区域或基质类型以外的来源指标。在本文中，我们介绍了一种基于 ASTM D7363-13a 的扩展分析方法，我们对其进行了适应，以用于气相色谱三重四极杆质谱仪器。与 ASTM 方法相比，这些修改提高了选择性和灵敏度。我们在方法中添加了五个烷基化系列。然后，我们将该方法应用于 22 个独立的法医比值。我们使用经过认证的参考材料和已知环境样本评估了该方法和法医比值。该分析方法和十三个 PAH 比值被发现可以准确预测 PAH 的来源。
