Petru E, Schmähl D
Institute of Toxicology and Chemotherapy, German Cancer Research Center, Heidelberg.
J Cancer Res Clin Oncol. 1988;114(2):183-5. doi: 10.1007/BF00417834.
The results of clinical studies dealing with first and second line chemotherapy of metastatic breast cancer published between 1975 and early 1986 which involved 9350 women were reviewed. Our special aim was to evaluate combination chemotherapy and its influence on overall survival in late stage breast cancer patients. No significant improvement in overall survival times was found in this selected group of patients who were treated with intense palliative chemotherapy.
对1975年至1986年初发表的涉及9350名女性的转移性乳腺癌一线和二线化疗临床研究结果进行了回顾。我们的特别目的是评估联合化疗及其对晚期乳腺癌患者总生存期的影响。在接受强化姑息化疗的这组选定患者中,未发现总生存时间有显著改善。