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诊断与侵入性分期:非手术性侵入性纵隔分期。支气管内超声检查。

Diagnosis and invasive staging: Non-surgical invasive mediastinal staging. Endobronchial ultrasound.

作者信息

Pajares Virginia, Torrego Alfons, Martínnez-Téllez Elisabeth, Trujillo-Reyes Juan Carlos

机构信息

Respiratory Medicine.

Biomedical Research Institute Sant Pau (IIB-Sant Pau), Barcelona, Spain.

出版信息

J Clin Transl Res. 2020 Sep 2;6(4):121-126. eCollection 2020 Oct 29.

PMID:33521372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7837739/
Abstract

UNLABELLED

The diagnosis and staging of lung cancer are an important process that identifies treatment options and guides disease prognosis. Therefore, an accurate mediastinal lymph node (LN) staging is required not only to offer the appropriate treatment but also to avoid unnecessary invasive procedures. At present, endobronchial ultrasound (EBUS)-transbronchial needle aspiration is the preferred modality for sampling mediastinal lymph nodes because of its minimally invasive nature and high diagnostic yield. In this review, we discuss the utility of EBUS in mediastinal LN staging of non-small cell lung cancer (NSCLC).

RELEVANCE FOR PATIENTS

The use of EBUS-TBNA in the diagnosis of mediastinal and hilar LN pathology has become in an essential endoscopic technique and the first step for staging of lung cancer.

摘要

未标注

肺癌的诊断和分期是确定治疗方案并指导疾病预后的重要过程。因此,准确的纵隔淋巴结(LN)分期不仅是为了提供合适的治疗,也是为了避免不必要的侵入性操作。目前,由于其微创性和高诊断率,支气管内超声(EBUS)引导下经支气管针吸活检是纵隔淋巴结采样的首选方式。在本综述中,我们讨论了EBUS在非小细胞肺癌(NSCLC)纵隔LN分期中的应用。

对患者的相关性

EBUS-TBNA在纵隔和肺门LN病变诊断中的应用已成为一项重要的内镜技术,也是肺癌分期的第一步。

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本文引用的文献

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Lung Cancer. 2020 Apr;142:9-12. doi: 10.1016/j.lungcan.2020.01.014. Epub 2020 Jan 13.
2
Next-Generation Sequencing for Genotyping of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration Samples in Lung Cancer.下一代测序技术在肺癌支气管内超声引导经支气管针吸活检样本基因分型中的应用。
Ann Thorac Surg. 2019 Jul;108(1):219-226. doi: 10.1016/j.athoracsur.2019.02.010. Epub 2019 Mar 15.
3
Adequacy of EBUS-TBNA specimen for mutation analysis of lung cancer.
EBUS-TBNA标本用于肺癌突变分析的充分性。
Clin Respir J. 2019 Feb;13(2):92-97. doi: 10.1111/crj.12985.
4
Ten Years of Linear Endobronchial Ultrasound: Evidence of Efficacy, Safety and Cost-effectiveness.线性支气管内超声十年:疗效、安全性及成本效益证据
Arch Bronconeumol. 2016 Feb;52(2):96-102. doi: 10.1016/j.arbres.2015.08.007. Epub 2015 Nov 10.
5
Endosonography for lung cancer staging: predictors for false-negative outcomes.用于肺癌分期的腔内超声检查:假阴性结果的预测因素
Lung Cancer. 2015 Dec;90(3):451-6. doi: 10.1016/j.lungcan.2015.09.020. Epub 2015 Sep 25.
6
Combined endobronchial and oesophageal endosonography for the diagnosis and staging of lung cancer. European Society of Gastrointestinal Endoscopy (ESGE) Guideline, in cooperation with the European Respiratory Society (ERS) and the European Society of Thoracic Surgeons (ESTS).联合支气管内和食管内镜超声检查用于肺癌的诊断和分期。欧洲胃肠内镜学会(ESGE)指南,与欧洲呼吸学会(ERS)和欧洲胸外科医师学会(ESTS)合作制定。
Eur Respir J. 2015 Jul;46(1):40-60. doi: 10.1183/09031936.00064515. Epub 2015 Jun 1.
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