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并发胸骨骨折:肋骨骨折患者肺部并发症和死亡率增加的预示因素。

Concomitant Sternal Fractures: Harbinger of Worse Pulmonary Complications and Mortality in Patients With Rib Fractures.

机构信息

Division of General Surgery, Department of Surgery, 6429Stanford University, CA, USA.

Department of Epidemiology and Population Health, 6429Stanford University, CA, USA.

出版信息

Am Surg. 2022 Jun;88(6):1201-1206. doi: 10.1177/0003134821991978. Epub 2021 Jan 31.

Abstract

BACKGROUND

Sternal and rib fractures are common concomitant injuries. However, the impact of concurrent sternal fractures on clinical outcomes of patients with rib fractures is unclear. We aimed to unveil the pulmonary morbidity and mortality impact of concomitant sternal fractures among patients with rib fractures.

METHODS

We identified adult patients admitted with traumatic rib fractures with vs. without concomitant sternal fractures using the 2012-2014 National Inpatient Sample (NIS). After 2:1 propensity score matching and adjustment for residual imbalances, we compared risk of pulmonary morbidity and mortality between patients with vs. without concomitant sternal fractures. Subgroup analysis in patients with flail chest assessed whether sternal fractures modify the association between undergoing surgical stabilization of rib fractures (SSRF) and pulmonary morbidity or mortality.

RESULTS

Of 475 710 encounters of adults admitted with rib fractures, 24 594 (5%) had concomitant sternal fractures. After 2:1 propensity score matching, patients with concomitant sternal fractures had 70% higher risk (95% CI: 50-90% higher, < 0.001) of undergoing tracheostomy, 40% higher risk (30-50% higher, <.001) of undergoing intubation, and 20% higher risk of respiratory failure (10-30% higher, <.001) and mortality (10-40% higher, =.007). Subgroup analysis of 8600 patients with flail chest showed concomitant sternal fractures did not impact the association between undergoing SSRF and any pulmonary morbidity or mortality.

CONCLUSION

Concomitant sternal fractures are associated with increased risk for pulmonary morbidity and mortality among patients with rib fractures. However, our findings are limited by a binary definition of sternal fractures, which encompasses heterogeneous injury patterns with likely variable clinical relevance.

摘要

背景

胸骨和肋骨骨折是常见的伴随损伤。然而,并发胸骨骨折对肋骨骨折患者临床结局的影响尚不清楚。我们旨在揭示并发胸骨骨折对肋骨骨折患者肺部发病率和死亡率的影响。

方法

我们使用 2012-2014 年全国住院患者样本(NIS),确定了因创伤性肋骨骨折住院且伴有或不伴有并发胸骨骨折的成年患者。在进行 2:1 倾向评分匹配和调整残余不平衡后,我们比较了伴有和不伴有并发胸骨骨折的患者发生肺部发病率和死亡率的风险。在连枷胸患者中进行亚组分析,评估胸骨骨折是否改变了行肋骨骨折手术固定(SSRF)与肺部发病率或死亡率之间的关系。

结果

在 475710 例因肋骨骨折住院的成年患者中,有 24594 例(5%)伴有并发胸骨骨折。在进行 2:1 倾向评分匹配后,伴有并发胸骨骨折的患者行气管切开术的风险增加 70%(95%CI:50-90%更高, <0.001),行气管插管的风险增加 40%(30-50%更高, <.001),呼吸衰竭的风险增加 20%(10-30%更高, <.001),死亡率增加 20%(10-40%更高, =.007)。在 8600 例连枷胸患者的亚组分析中,并发胸骨骨折并未影响行 SSRF 与任何肺部发病率或死亡率之间的关系。

结论

并发胸骨骨折与肋骨骨折患者肺部发病率和死亡率增加相关。然而,我们的发现受到胸骨骨折的二元定义的限制,该定义包含了可能具有不同临床相关性的异质损伤模式。

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