Department of Inorganic and Analytical Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland.
Crit Rev Food Sci Nutr. 2022;62(17):4607-4621. doi: 10.1080/10408398.2021.1877110. Epub 2021 Feb 1.
Nowadays, topics related to the proper nutrition of the body, which requires a complex of compounds and supplementation of these ingredients have undoubtedly gained popularity, so it should come as no surprise that there is a widespread interest in vitamin D in science, medicine, analytics and nutrition. In the world of developing technologies, new directions of physiological action of this vitamin on the body are being discovered. Issues related to the demand for vitamin D in various populations and its sources in food, the appropriate form of supplementation, safety and toxicity are extremely important. The present manuscript focuses on the concise evaluation of key data in the field of vitamin D. Structure and physicochemical properties, demand and delivery trails, deficiency and its diagnosis, supplementation, interactions of vitamin D with supplements and drugs are discussed. Attention has also been paid to the methods of vitamin D analysis in various matrices, which allow for an accurate and precise quality assessment of dietary supplements, drugs and food products. The presented information allows deeper understanding of the mechanisms responsible for the development of many diseases in the context of vitamin D levels.
如今,与人体合理营养相关的话题,即需要多种化合物的复合以及这些成分的补充,无疑已经变得非常热门,因此,人们对科学界、医学界、分析学和营养学领域的维生素 D 广泛关注也就不足为奇了。在不断发展的技术世界中,人们正在发现这种维生素对人体的新的生理作用方向。与各种人群对维生素 D 的需求及其在食物中的来源、适当的补充形式、安全性和毒性相关的问题极为重要。本文重点对维生素 D 领域的关键数据进行了简洁评估。讨论了维生素 D 的结构和理化性质、需求和输送试验、缺乏及其诊断、补充、与补充剂和药物的相互作用等内容。还特别关注了各种基质中维生素 D 分析的方法,这些方法可以对膳食补充剂、药物和食品进行准确和精确的质量评估。所呈现的信息可以帮助深入理解在维生素 D 水平背景下许多疾病的发展机制。