Acta Chim Slov. 2020 Sep;67(3):710-719.
The inhibition behavior of metoprolol tablet on steel alloy (st37) in 1 M hydrochloric acid and 0.5 M sulfuric acid solutions were studied by three methods (potentiodynamic polarization, electrochemical impedance spectroscopy, and scanning electronic microscopy, SEM). The obtained parameters revealed that different amounts of metoprolol drug inhibited the corrosion of mild steel in the acid solutions of HCl and H2SO4. The corrosion resistance of the alloy increased with the increase in the concentration of metoprolol up to 300 ppm but was reduced by increasing the temperature. The derived parameters from polarization curves indicated that the drug is a mixed type inhibitor. The results obtained from the different methods are consistent with each other. The adsorption of metoprolol was found to be physical, exothermic, and spontaneous, and also fitted the Langmuir adsorption model. SEM micrographs are in accordance with the adsorption performance of the tablet.
采用三种方法（动电位极化、电化学阻抗谱和扫描电子显微镜，SEM）研究了美托洛尔片剂在 1M 盐酸和 0.5M 硫酸溶液中对钢合金（st37）的抑制行为。获得的参数表明，不同剂量的美托洛尔药物抑制了盐酸和硫酸溶液中低碳钢的腐蚀。随着美托洛尔浓度的增加，合金的耐腐蚀性增加，但随着温度的升高而降低。从极化曲线得出的参数表明，该药物是一种混合型抑制剂。不同方法得到的结果相互一致。发现美托洛尔的吸附是物理的、放热的和自发的，并且也符合 Langmuir 吸附模型。SEM 显微照片与片剂的吸附性能一致。
